About: Phylogenetic characterization of circulating Dengue and Alkhumra Hemorrhagic Fever viruses in western Saudi Arabia and lack of evidence of Zika virus in the region: A retrospective study, 2010‐2015

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About: Phylogenetic characterization of circulating Dengue and Alkhumra Hemorrhagic Fever viruses in western Saudi Arabia and lack of evidence of Zika virus in the region: A retrospective study, 2010‐2015 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Phylogenetic characterization of circulating Dengue and Alkhumra Hemorrhagic Fever viruses in western Saudi Arabia and lack of evidence of Zika virus in the region: A retrospective study, 2010‐2015
Creator	Azhar, Esam Charrel, Remi Hashem, M Hassan, Ahmed El-Kafrawy, A Al-Saeed, Moneerah Al-Subhi, L Alshawdari, M Alsultan, Arwa Anwar, \| Ben Helaby, Huda Farraj, A Mustafa, \| Othman, Norah Sherif, \| Suha, \| Tagreed, \|
source	Medline; PMC
abstract	Flaviviruses represent a global public health concern. They consist of ∼70 viruses with almost half of them causing human diseases with unspecified febrile illnesses. Cities in western Saudi Arabia are endemic for viruses (DENV) with sporadic infections due to Alkhumra hemorrhagic fever virus (AHFV). They also represent a major destination for travelers coming for annual religious pilgrimages (Hajj and Umrah) from all over the world. However, whether other flaviviruses are circulating is not known because of the limited number of surveillance studies. Here, we retrospectively screened 690 samples for flaviviruses in samples from patients with unexplained febrile illnesses between 2010 and 2015 in western Saudi Arabia using a pan‐flaviviruses RT‐PCR assay. Despite Zika virus RNA was not detected, this study confirms circulation and/or sporadic spread of DENV‐2, DENV‐3, and AHFV, higher prevalence of DENV‐2, and a role for visitors from DENV endemic countries in DENV importation into the Kingdom. Further analysis also showed very low genetic diversity of AHFV confirming its slow microevolution. Accordingly, continuous and prospective surveillance for flaviviruses using such assay are warranted in Saudi Arabia which receives millions of Muslims annually to implement effective control measures in light of the global widespread and outbreaks of several flaviviruses.
has issue date	2017-03-08(xsd:dateTime)
bibo:doi	10.1002/jmv.24785
bibo:pmid	28198548
has license	no-cc
sha1sum (hex)	afaba219bb1ef133dc868c04c0bcccdcae24a629
schema:url	https://doi.org/10.1002/jmv.24785
resource representing a document's title	Phylogenetic characterization of circulating Dengue and Alkhumra Hemorrhagic Fever viruses in western Saudi Arabia and lack of evidence of Zika virus in the region: A retrospective study, 2010‐2015
has PubMed Central identifier	PMC7167144
has PubMed identifier	28198548
schema:publication	J Med Virol
resource representing a document's body	covid:afaba219bb1ef133dc868c04c0bcccdcae24a629#body_text
is schema:about of	named entity 'They' named entity 'infections' named entity 'retrospective study' named entity 'SAUDI ARABIA' named entity 'VIRUSES' named entity 'CAUSING' named entity 'SURVEILLANCE' named entity 'STUDIES' named entity 'FLAVIVIRUSES' named entity 'UNSPECIFIED' named entity 'REPRESENT' covid:arg/afaba219bb1ef133dc868c04c0bcccdcae24a629 named entity 'Tick-borne encephalitis virus' named entity 'virology' named entity 'Flavivirus' named entity 'arboviruses' named entity 'AHFV' named entity 'Hilden' named entity 'DENV' named entity 'Saudi Arabia' named entity 'health concern' named entity 'consist' named entity 'Hajj' named entity 'virus' named entity 'amino acid' named entity 'bat' named entity 'screening tool' named entity 'flaviviruses' named entity 'highly conserved' named entity 'viral species' named entity 'Qiagen' named entity 'pathogens' named entity 'causing' named entity 'Hajj' named entity 'global public health' named entity 'Saudi Arabia' named entity 'DENV' named entity 'human diseases' named entity 'Phylogenetic' named entity 'Dengue' named entity 'fever' named entity 'viruses' named entity 'vertebrate' named entity 'RNA' named entity 'viruses' named entity 'flaviviruses' named entity 'JEV' named entity 'Alkhumra hemorrhagic fever virus' named entity 'DENV' named entity 'RVFV' named entity 'hemorrhagic fever' named entity 'tick' named entity 'WNV' named entity 'arboviruses' named entity 'epidemiological studies' named entity 'real-time RT-PCR' named entity 'Makkah' named entity 'mosquito' named entity 'RT-PCR' named entity 'Zika infection' named entity 'AHFV' named entity 'diagnostic tests' named entity 'microevolution' named entity 'endemic' named entity 'Flaviviruses'

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