About: Do olfactory and gustatory psychophysical scores have prognostic value in COVID-19 patients? A prospective study of 106 patients

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Do olfactory and gustatory psychophysical scores have prognostic value in COVID-19 patients? A prospective study of 106 patients Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Do olfactory and gustatory psychophysical scores have prognostic value in COVID-19 patients? A prospective study of 106 patients
Creator	Hopkins, Claire De Riu, Giacomo Giovanditto, Federica Lechien, Jerome Petrocelli, Marzia Piombino, Pasquale Rizzo, Davide Salzano, Giovanni Saussez, Sven Soma, Damiano Vaira, Luigi
Source	Medline; PMC
abstract	BACKGROUND: The lack of objective data makes it difficult to establish the prognostic value of chemosensitive disorders in coronavirus disease 2019 (COVID-19) patients. We aimed to prospectively monitor patients diagnosed with COVID-19 to see if the severity of olfactory and gustatory dysfunction associates with subsequent disease severity. METHODS: Multicentre prospective study that recruited 106 COVID-19 subjects at diagnosis. Chemosensitive functions were assessed with psychophysical tests within 4 days of clinical onset, at 10 and 20 days. Daily body temperature and oxygen saturation were recorded as markers of disease severity alongside need for hospitalisation. The correlation between olfactory and gustatory scores and disease severity was assessed with linear regression analysis. RESULTS: At T0, 71 patients (67%) presented with olfactory dysfunction while gustatory impairment was detected in 76 cases (65.6%). Chemosensitive disorders gradually improved over the observation period. No significant correlations were found between T0 chemosensitive scores and final disease severity. The correlation between olfactory scores and fever proved significant at T2 (p = 0.05), while the relationship with gustatory scores was significant at T1 (p = 0.01) and T2 (p < 0.001), however neither was clinically relevant. The correlation between chemosensitive scores and oxygen saturation was significant only for taste at T2 (p < 0.001). Logistic regression analysis found significant correlations between olfactory impairment severity and need for hospitalization at T2 (OR 3.750, p = 0.005). CONCLUSIONS: Initial objective olfactory and gustatory scores do not seem to have a significant prognostic value in predicting the severity of the COVID-19 course; however, persistence of olfactory dysfunction at 20 days, associated with a more severe course. Unfortunately, olfactory and gustatory dysfunction do not seem to hold prognostic value at the time of initial diagnosis.
has issue date	2020-08-06(xsd:dateTime)
bibo:doi	10.1186/s40463-020-00449-y
bibo:pmid	32762737
has license	cc-by
sha1sum (hex)	b1c17f9eaed47a9e5649b0ab425092af854612fa
schema:url	https://doi.org/10.1186/s40463-020-00449-y
resource representing a document's title	Do olfactory and gustatory psychophysical scores have prognostic value in COVID-19 patients? A prospective study of 106 patients
has PubMed Central identifier	PMC7406962
has PubMed identifier	32762737
schema:publication	J Otolaryngol Head Neck Surg
resource representing a document's body	covid:b1c17f9eaed47a9e5649b0ab425092af854612fa#body_text
is schema:about of	named entity 'prognostic' named entity 'GUSTATORY' named entity 'HAVE' named entity 'olfactory' named entity 'coronavirus disease 2019' named entity 'anosmia' named entity 'COVID' named entity 'COVID' named entity 'recall bias' named entity 'pulmonary disease' named entity 'statistically significant' named entity 'anosmia' named entity 'comorbidities' named entity 'public health' named entity 'critical stage' named entity 'gustatory' named entity 'hyposmia' named entity 'clinical outcome' named entity 'gustatory' named entity 'self-reported' named entity 'COVID' named entity 'independent ethics committee' named entity 'olfactory dysfunction' named entity 'study design' named entity 'hospital capacity' named entity 'olfactory' named entity 'discrimination' named entity 'alcohol' named entity 'gustatory' named entity 'Linear regression' named entity 'gustatory' named entity 'Crosstab' named entity 'hyposmia' named entity 'OSS' named entity 'linear regression' named entity 'symptom' named entity 'fever' named entity 'olfactory' named entity 'hypogeusia' named entity 'logistic regression' named entity 'prospective study' named entity 'COVID-19' named entity 'olfactory' named entity 'olfactory' named entity 'psychophysical' named entity 'prospective study' named entity 'markers of disease' named entity 'crosstab' named entity 'anosmia' named entity 'informed consent' named entity 'olfactory' named entity 'statistical significant' named entity 'self-report' named entity 'gustatory' named entity 'mouse model' named entity 'olfactory' named entity 'anosmia' named entity 'olfactory' named entity 'olfactory' named entity 'olfactory' named entity 'oxygen saturation' named entity 'clinical outcomes' named entity 'data collected' named entity 'Italian' named entity 'olfactory' named entity 'hyposmia' named entity 'retrospective studies' named entity 'evolution' named entity 'COVID' named entity 'gustatory' named entity 'oxygen saturations'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software