About: Quality Evaluation of Juniperus rigida Sieb. et Zucc. Based on Phenolic Profiles, Bioactivity, and HPLC Fingerprint Combined with Chemometrics

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Quality Evaluation of Juniperus rigida Sieb. et Zucc. Based on Phenolic Profiles, Bioactivity, and HPLC Fingerprint Combined with Chemometrics Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Quality Evaluation of Juniperus rigida Sieb. et Zucc. Based on Phenolic Profiles, Bioactivity, and HPLC Fingerprint Combined with Chemometrics
Creator	Li, Dengwu Liu, Zehua Wang, Dongmei Zhang, Shuai Chan, Kok, Gan Gafner, Stefan
Source	PMC
abstract	Juniperus rigida (J. rigida) which is endemic to East Asia, has traditionally been used as an ethnomedicinal plant in China. This study was undertaken to evaluate the quality of J. rigida samples derived from 11 primary regions in China. Ten phenolic compounds were simultaneously quantified using reversed-phase high-performance liquid chromatography (RP-HPLC), and chlorogenic acid, catechin, podophyllotoxin, and amentoflavone were found to be the main compounds in J. rigida needles, with the highest contents detected for catechin and podophyllotoxin. J. rigida from Jilin (S9, S10) and Liaoning (S11) exhibited the highest contents of phenolic profiles (total phenolics, total flavonoids and 10 phenolic compounds) and the strongest antioxidant and antibacterial activities, followed by Shaanxi (S2, S3). A similarity analysis (SA) demonstrated substantial similarities in fingerprint chromatograms, from which 14 common peaks were selected. The similarity values varied from 0.85 to 0.98. Chemometrics techniques, including hierarchical cluster analysis (HCA), principal component analysis (PCA), and discriminant analysis (DA), were further applied to facilitate accurate classification and quantification of the J. rigida samples derived from the 11 regions. The results supported HPLC data showing that all J. rigida samples exhibit considerable variations in phenolic profiles, and the samples were further clustered into three major groups coincident with their geographical regions of origin. In addition, two discriminant functions with a 100% discrimination ratio were constructed to further distinguish and classify samples with unknown membership on the basis of eigenvalues to allow optimal discrimination among the groups. Our comprehensive findings on matching phenolic profiles and bioactivities along with data from fingerprint chromatograms with chemometrics provide an effective tool for screening and quality evaluation of J. rigida and related medicinal preparations.
has issue date	2017-04-19(xsd:dateTime)
bibo:doi	10.3389/fphar.2017.00198
bibo:pmid	28469573
has license	cc-by
sha1sum (hex)	b515cc5df8df49a37037106bfe3d94a2370e30bd
schema:url	https://doi.org/10.3389/fphar.2017.00198
resource representing a document's title	Quality Evaluation of Juniperus rigida Sieb. et Zucc. Based on Phenolic Profiles, Bioactivity, and HPLC Fingerprint Combined with Chemometrics
has PubMed Central identifier	PMC5395569
has PubMed identifier	28469573
schema:publication	Front Pharmacol
resource representing a document's body	covid:b515cc5df8df49a37037106bfe3d94a2370e30bd#body_text
is schema:about of	named entity 'EVALUATION' named entity 'QUALITY' named entity 'BIOACTIVITY' named entity 'BASED' named entity 'HPLC' named entity 'MAIN' named entity 'USED' named entity 'RATIO' named entity 'ACCURATE' named entity 'ALLOW' named entity 'EFFECTIVE' named entity 'EIGENVALUES' named entity 'DISCRIMINATION' named entity 'LIQUID CHROMATOGRAPHY ' named entity 'ANTIOXIDANT' named entity 'PHENOLICS' named entity 'USING' named entity 'FINGERPRINT' named entity 'FLAVONOIDS' named entity 'TOTAL' named entity 'HIERARCHICAL CLUSTER ANALYSIS' named entity 'DISCRIMINANT ANALYSIS' named entity 'RESULTS' named entity 'INCLUDING' named entity 'S10' named entity 'CONSIDERABLE' named entity 'PRIMARY' named entity 'ANALYSIS' named entity 'REGIONS' named entity 'THEIR' named entity 'COMPREHENSIVE' named entity 'CHLOROGENIC ACID' named entity 'MATCHING' named entity 'COMMON' named entity 'SIMILARITY' named entity 'UNKNOWN' named entity 'PHENOLIC' named entity 'CLASSIFY' named entity 'SAMPLES' named entity 'FINDINGS' named entity 'CLASSIFICATION' named entity 'PHENOLIC' named entity 'QUALITY' named entity 'VALUES' named entity 'TECHNIQUES' named entity 'SCREENING' named entity 'CONSTRUCTED' named entity 'ANTIBACTERIAL' named entity 'PROVIDE' named entity 'CATECHIN' named entity 'SUPPORTED' named entity 'CHINA' named entity 'CLUSTERED' named entity 'ADDITION' named entity 'AMENTOFLAVONE' named entity 'PLANT' named entity 'FOLLOWED BY' named entity 'REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY' named entity 'EVALUATION' named entity 'SIEB' named entity 'FINGERPRINT' named entity 'COMBINED' named entity 'CHEMOMETRICS' named entity 'PODOPHYLLOTOXIN' named entity 'OUR' named entity 'GROUPS' named entity '100%' named entity 'EXHIBIT' named entity 'DATA' named entity 'TOOL' named entity 'EVALUATE' named entity 'MEMBERSHIP' named entity 'CHEMOMETRICS' named entity 'QUANTIFICATION' named entity 'RELATED'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software