About: Evaluation of Enzyme-Linked Immunoassay and Colloidal Gold- Immunochromatographic Assay Kit for Detection of Novel Coronavirus (SARS-Cov-2) Causing an Outbreak of Pneumonia (COVID-19)

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About: Evaluation of Enzyme-Linked Immunoassay and Colloidal Gold- Immunochromatographic Assay Kit for Detection of Novel Coronavirus (SARS-Cov-2) Causing an Outbreak of Pneumonia (COVID-19) Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Evaluation of Enzyme-Linked Immunoassay and Colloidal Gold- Immunochromatographic Assay Kit for Detection of Novel Coronavirus (SARS-Cov-2) Causing an Outbreak of Pneumonia (COVID-19)
Creator	Xiang, Jie Liu, Ting Huang, Shuang Li, Hongze Lin, Chenyao Shen, Changxin Yan, Mingzhe
source	MedRxiv
abstract	Abstract BACKGROUND: In December 2019, a novel coronavirus (SARS-CoV-2) infected pneumonia (COVID-19) occurred in Wuhan, China. Travel-associated cases have also been reported in other countries. The number of cases has increased rapidly but laboratory diagnosis is limited. METHODS: We collect two groups of cases diagnosed with COVID-19 for experiments. One group collected 63 samples for Enzyme-linked immunosorbent assay (ELISA) IgG and IgM antibodies. The other group collected 91 plasma samples for colloidal gold-immunochromatographic assay (GICA). RESULTS: The sensitivity of the combined ELISA IgM and ELISA IgG detection was 55/63 ( 87.3%), The sensitivity of the combined GICA IgM and GICA IgG detection was 75/91 ( 82.4%), Both methods are negative for healthy controls, specificity of 100% .There is no significant difference between the sensitivity of between ELISA and GICA (IgM+ IgG). CONCLUSIONS: ELISA and GICA for specific IgM and IgG antibodies are conventional serological assays, they are simple, fast, and safe, the results can be used for clinical reference, and the huge clinical diagnosis and treatment pressure can be greatly relieved.
has issue date	2020-03-01(xsd:dateTime)
bibo:doi	10.1101/2020.02.27.20028787
has license	medrxiv
sha1sum (hex)	b579c3547bba2a33057373d57b7c05f37dd4cfc3
schema:url	https://doi.org/10.1101/2020.02.27.20028787
resource representing a document's title	Evaluation of Enzyme-Linked Immunoassay and Colloidal Gold- Immunochromatographic Assay Kit for Detection of Novel Coronavirus (SARS-Cov-2) Causing an Outbreak of Pneumonia (COVID-19)
resource representing a document's body	covid:b579c3547bba2a33057373d57b7c05f37dd4cfc3#body_text
is schema:about of	named entity 'areas' named entity 'Outside' named entity 'assay' named entity 'rapidly' named entity 'CONTROLS' named entity 'NUMBER OF' named entity 'RAPIDLY' named entity 'COLLOIDAL GOLD' named entity 'CASES REPORTED' named entity 'CASES' named entity 'COMBINED' named entity 'CHINA' named entity 'NOVEL CORONAVIRUS' named entity 'CAUSING' named entity 'OUTBREAK' named entity 'METHODS' named entity 'WUHAN' named entity 'SAFE' named entity 'OCCURRED' named entity 'SPREAD' named entity 'COLLECT' named entity 'LOST' named entity 'COLLECTED' named entity 'SEROLOGICAL' named entity 'REPORTED' named entity 'OTHER GROUP' named entity 'TRAVEL' named entity 'HEALTHY' named entity 'ASSOCIATED' named entity 'BACKGROUND' named entity 'RIGHTS' named entity 'LIMITED' named entity 'EVALUATION' named entity 'ASSAY KIT' named entity 'ASSAY' named entity 'CONFIRMED' named entity 'USED' named entity 'ENZYME' named entity 'DETECTION' named entity 'NOVEL CORONAVIRUS' named entity 'DEATH' named entity 'REUSE' named entity 'OUTSIDE' named entity 'IGM' named entity 'ENZYME-LINKED IMMUNOSORBENT ASSAY' named entity 'CONVENTIONAL' named entity 'HAVE' named entity 'GICA' named entity 'GROUPS' named entity 'IGG' named entity 'RESULTS' named entity 'SAMPLES' named entity 'TREATMENT' named entity 'DIFFERENCE' named entity 'INCREASED' named entity 'PNEUMONIA' named entity 'MOST OF' named entity 'SIMPLE' named entity 'ANTIBODIES' named entity 'SENSITIVITY' named entity 'GROUP' named entity 'DEATHS' named entity 'SPECIFIC' named entity 'CONCLUSIONS' named entity 'COUNTRIES' named entity 'LIVES' named entity 'LABORATORY DIAGNOSIS' named entity 'SIGNIFICANT' named entity 'FEBRUARY' named entity '100%' named entity 'NEGATIVE' named entity '2019' named entity 'AREAS' named entity 'CLINICAL' named entity 'EXPERIMENTS' named entity 'ELISA' named entity 'DECEMBER' named entity 'CAUSED BY' named entity 'CLINICAL DIAGNOSIS'

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