About: Role of early diagnosis for a noninvasive treatment of pulmonary thromboembolism in leukemic children

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About: Role of early diagnosis for a noninvasive treatment of pulmonary thromboembolism in leukemic children Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Role of early diagnosis for a noninvasive treatment of pulmonary thromboembolism in leukemic children
Creator	Communication, Short Arrigo, C Biagi, Biagi, E Gerardo, Marchi, P Marraro, G Masera, Masera, G Monza, Italy Riva, A Rovelli, A Servizio Di Anestesiologia, San Uderzo, Uderzo, C
source	PMC
abstract	Pulmonary thromboembolism (PTE) in leukemic children undergoing intensive chemotherapy should be promptly recognized so that specific therapy can be started. Our experience with the two cases reported here has led us to propose guidelines for the treatment of initial PTE in a pediatric hematology unit. Two children with leukemia developed PTE, the first during the relapse for acute lymphoblastic leukemia and the second at the onset of acute promyelocytic leukemia. In both cases, the diagnosis of PTE was based on clinical assessment of sudden acute respiratory failure with positive pulmonary perfusional scintigraphy in spite of a negative chest X-ray. The subintensive supervision consisted of instrumental monitoring with the assistance of an intensive care anesthetist. The clinical monitoring was based on the serial registration of respiratory rate, cardiac rate, SaO(2) and body temperature. The thrombolytic therapy, together with heparin prophylaxis, was successfully administered in the hematology ward without the need for intensive care support (i.e. mechanical ventilation). The success of the treatment was documented by the criterion of a return to the normal cardiorespiratory parameters a few hours after the start of the thrombolytic treatment. Furthermore, a chest CT scan in case 1 and an arteriography in case 2 confirmed the PTE-related hypoperfusion. On the basis of this experience, the authors point out that in the course of acute respiratory failure in leukemic children, the combination of a negative chest X-ray and a positive pulmonary perfusional scintigraphy (compared whenever possible with ventilatory scintigraphy) in the presence of a negative CT scan could be a reliable diagnostic tool for PTE. This pathology should be treated promptly and with specific therapy to avoid progression to a severe, massive PTE.
has issue date	2014-02-08(xsd:dateTime)
bibo:doi	10.1007/s005200050102
bibo:pmid	9322356
has license	no-cc
sha1sum (hex)	b625e36e4c217d00e2343aebfd7b1ce3dbc71e7c
schema:url	https://doi.org/10.1007/s005200050102
resource representing a document's title	Role of early diagnosis for a noninvasive treatment of pulmonary thromboembolism in leukemic children
has PubMed Central identifier	PMC7102284
has PubMed identifier	9322356
schema:publication	Support Care Cancer
resource representing a document's body	covid:b625e36e4c217d00e2343aebfd7b1ce3dbc71e7c#body_text
is schema:about of	named entity 'pulmonary thromboembolism' named entity 'pulmonary thromboembolism' named entity 'leukemic' named entity 'therapy' named entity 'scintigraphy' named entity '20 months' named entity 'body temperature' named entity 'opacity' named entity 'leukemic' named entity 'respiratory rate' named entity 'coagulation abnormalities' named entity 'bone marrow transplantation' named entity 'arteriography' named entity 'angiography' named entity 'fever' named entity 'hypoperfusion' named entity 'scintigraphy' named entity 'hyperalimentation' named entity 'ARF' named entity 'perfusion' named entity 'chemotherapy' named entity 'acute respiratory failure' named entity 'scintigraphy' named entity 'CVC' named entity 'CVC' named entity 'scintigraphy' named entity 'chest X-ray' named entity 'hematology' named entity 'thrombosis' named entity 'malignant' named entity 'acute respiratory failure' named entity 'lysis' named entity 'antibiotic therapy' named entity 'relapse' named entity 'body temperature' named entity 'scintigraphy' named entity 'child died' named entity 'cytarabine' named entity 'endothelial cell' named entity 'lung embolism' named entity 'thromboembolic disease' named entity 'central venous' named entity 'endothelial' named entity 'anesthetist' named entity 'prognosis' named entity 'infusion' named entity 'heparin' named entity 'infusion' named entity 'chest CT scan' named entity 'respiratory rates' named entity 'pediatric' named entity 'Tachypnea' named entity 'intensive care unit' named entity 'hypoperfusion' named entity 'Thrombolytic therapy' named entity 'computerized tomography' named entity 'fibrin' named entity 'pediatric oncology' named entity 'adult respiratory distress syndrome' named entity 'thrombolytic' named entity 'oncologist' named entity 'congenital' named entity 'bone marrow aspiration' named entity 'leukemic' named entity 'chest Xray' named entity 'relapse' named entity 'amikacin'

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