About: Laboratory Diagnosis of SARS

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Laboratory Diagnosis of SARS
Creator	Lee, Nelson Wu, Alan Hui, David Li, Chi-Kong Ng, King-Cheung Lai, Sik-To Ng, Tak-Keung Yu, Wai-Cho To, Wing-Kin Sung, Joseph Chan, Chan, Paul Tam, John Hon, Ellis Lam, Rebecca Rickjason, C
Source	Medline; PMC
abstract	The virologic test results of 415 patients with severe acute respiratory syndrome (SARS) were examined. The peak detection rate for SARS-associated coronavirus occurred at week 2 after illness onset for respiratory specimens, at weeks 2 to 3 for stool or rectal swab specimens, and at week 4 for urine specimens. The latest stool sample that was positive by reverse transcription–polymerase chain reaction (RT-PCR) was collected on day 75 while the patient was receiving intensive care. Tracheal aspirate and stool samples had a higher diagnostic yield (RT-PCR average positive rate for first 2 weeks: 66.7% and 56.5%, respectively). Pooled throat and nasal swabs, rectal swab, nasal swab, throat swab, and nasopharyngeal aspirate specimens provided a moderate yield (29.7%–40.0%), whereas throat washing and urine specimens showed a lower yield (17.3% and 4.5%). The collection procedures for stool and pooled nasal and throat swab specimens were the least likely to transmit infection, and the combination gave the highest yield for coronavirus detection by RT-PCR. Positive virologic test results in patient groups were associated with mechanical ventilation or death (p < 0.001), suggesting a correlation between viral load and disease severity.
has issue date	2004-05-01(xsd:dateTime)
bibo:doi	10.3201/eid1005.030682
bibo:pmid	15200815
has license	no-cc
sha1sum (hex)	b7f1dcfe8b12d6b8a548db0de597cbef95712d9c
schema:url	https://doi.org/10.3201/eid1005.030682
resource representing a document's title	Laboratory Diagnosis of SARS
has PubMed Central identifier	PMC3323215
has PubMed identifier	15200815
schema:publication	Emerg Infect Dis
resource representing a document's body	covid:b7f1dcfe8b12d6b8a548db0de597cbef95712d9c#body_text
is schema:about of	named entity 'EMERGING INFECTIOUS DISEASES' named entity 'average' named entity 'disease' named entity 'virologic' named entity 'Emerging Infectious Diseases' named entity 'Diagnosis' named entity 'LABORATORY DIAGNOSIS' named entity 'POSITIVE RATE' named entity 'TEST RESULTS' named entity 'RATE' named entity 'THROAT SWAB' named entity 'POLYMERASE CHAIN REACTION' named entity '415' named entity 'STOOL' named entity '4.5' named entity 'URINE' named entity 'COLLECTION' named entity 'ONSET' named entity 'REVERSE TRANSCRIPTION' named entity 'LATEST' named entity 'SARS-ASSOCIATED CORONAVIRUS' named entity 'RECEIVING' named entity 'HIGHEST' named entity 'DEATH' named entity 'EXAMINED' named entity 'MODERATE' named entity 'TO TRANSMIT' named entity '28P' named entity 'INTENSIVE CARE' named entity 'GAVE' named entity 'THE PEAK' named entity 'TRACHEAL ASPIRATE' named entity 'STOOL SAMPLE' named entity 'DAY' named entity 'DIAGNOSTIC YIELD' named entity 'WEEK' named entity '80%' named entity 'HIGHER' named entity 'PCR' named entity 'SAMPLES' named entity 'DETECTION' named entity 'VIROLOGIC' named entity 'CORRELATION' named entity 'PROVIDED' named entity 'RECTAL SWAB' named entity 'SPECIMENS' named entity 'COLLECTED' named entity 'AVERAGE' named entity 'INFECTION' named entity 'NASAL SWABS' named entity '2 WEEKS' named entity 'LIKELY' named entity 'THROAT WASHING' named entity 'YIELD' named entity '0.001' named entity 'RT-PCR' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'WWW' named entity 'PATIENT' named entity 'VIRAL LOAD' named entity 'NASAL SWAB' named entity 'POSITIVE' named entity 'POOLED' named entity 'COMBINATION' named entity 'CORONAVIRUS' named entity 'WEEKS'

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