About: Development of Small-Molecule Inhibitors Against Zika Virus Infection

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About: Development of Small-Molecule Inhibitors Against Zika Virus Infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Development of Small-Molecule Inhibitors Against Zika Virus Infection
Creator	Jiang, Shibo Wang, Lili Ying, Tianlei Rong, Lijun Yu, Fei Deng, Xiaoqian Liang, Ruiying Cheng, Gong Xiang, Rong Gao, Yaning Li, Yanbai Zhang, Yina Zhang, Xiang Li, Gao
Source	PMC
abstract	In recent years, the outbreak of infectious disease caused by Zika virus (ZIKV) has posed a major threat to global public health, calling for the development of therapeutics to treat ZIKV disease. Here, we have described the different stages of the ZIKV life cycle and summarized the latest progress in the development of small-molecule inhibitors against ZIKV infection. We have also discussed some general strategies for the discovery of small-molecule ZIKV inhibitors.
has issue date	2019-12-06(xsd:dateTime)
bibo:doi	10.3389/fmicb.2019.02725
bibo:pmid	31866959
has license	cc-by
sha1sum (hex)	c38bc4bdbec2199031430ac3813398806a13a0a9
schema:url	https://doi.org/10.3389/fmicb.2019.02725
resource representing a document's title	Development of Small-Molecule Inhibitors Against Zika Virus Infection
has PubMed Central identifier	PMC6909824
has PubMed identifier	31866959
schema:publication	Front Microbiol
resource representing a document's body	covid:c38bc4bdbec2199031430ac3813398806a13a0a9#body_text
is schema:about of	named entity 'ZIKA VIRUS INFECTION' named entity 'DEVELOPMENT' named entity 'GLOBAL' named entity 'GENERAL' named entity 'MOLECULE' named entity 'CAUSED BY' named entity 'DISEASE' named entity 'DISCOVERY' named entity 'INHIBITORS' named entity 'OUTBREAK' named entity 'A MAJOR' named entity 'STRATEGIES' named entity 'TREAT' named entity 'ZIKA VIRUS' named entity 'DIFFERENT' named entity 'THREAT' named entity 'CALLING' named entity 'MOLECULE' named entity 'SMALL' named entity 'PROGRESS' named entity 'STAGES' named entity 'SMALL' named entity 'HAVE' named entity 'THERAPEUTICS' named entity 'RECENT' named entity 'DEVELOPMENT' named entity 'PUBLIC HEALTH' named entity 'HERE' named entity 'DESCRIBED' named entity 'INHIBITORS' named entity 'INFECTIOUS DISEASE' named entity 'YEARS' named entity 'LIFE CYCLE' named entity 'ZIKV' named entity '13.1' named entity 'virus infection' named entity 'Zika virus' named entity 'Vero cells' named entity 'virus' named entity 'hydrophilic' named entity 'host cell' named entity 'N-terminal fragment' named entity 'Gly' named entity 'C-terminal' named entity 'infection' named entity 'plaque reduction' named entity 'natural phenol' named entity 'Puerto Rican' named entity 'virus' named entity 'enzyme assay' named entity 'Endosomes' named entity 'deficient mice' named entity 'ZIKV' named entity 'proteinase' named entity 'protein expression' named entity 'ZIKV' named entity 'cerebrospinal fluid' named entity 'pyridoxine' named entity 'viruses' named entity 'small molecule inhibitors' named entity 'ZIKV' named entity 'protease' named entity 'cilnidipine' named entity 'organoid' named entity 'forebrain' named entity 'lopinavir' named entity 'pharmacophore' named entity 'virus'

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