About: An emerging cyberinfrastructure for biodefense pathogen and pathogen

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	An emerging cyberinfrastructure for biodefense pathogen and pathogen–host data
Creator	Zhang, J Wu, C Moore, M Zhang, C Cammer, S Chen, Y Crasta, O Huang, H Jha, R Kenyon, R Liu, D Mazumder, R Mcgarvey, P Sobral, B Sullivan, D Sun, W Will, R Xue, T Yu, Q Zhang, Y
source	Medline; PMC
abstract	The NIAID-funded Biodefense Proteomics Resource Center (RC) provides storage, dissemination, visualization and analysis capabilities for the experimental data deposited by seven Proteomics Research Centers (PRCs). The data and its publication is to support researchers working to discover candidates for the next generation of vaccines, therapeutics and diagnostics against NIAID's Category A, B and C priority pathogens. The data includes transcriptional profiles, protein profiles, protein structural data and host–pathogen protein interactions, in the context of the pathogen life cycle in vivo and in vitro. The database has stored and supported host or pathogen data derived from Bacillus, Brucella, Cryptosporidium, Salmonella, SARS, Toxoplasma, Vibrio and Yersinia, human tissue libraries, and mouse macrophages. These publicly available data cover diverse data types such as mass spectrometry, yeast two-hybrid (Y2H), gene expression profiles, X-ray and NMR determined protein structures and protein expression clones. The growing database covers over 23 000 unique genes/proteins from different experiments and organisms. All of the genes/proteins are annotated and integrated across experiments using UniProt Knowledgebase (UniProtKB) accession numbers. The web-interface for the database enables searching, querying and downloading at the level of experiment, group and individual gene(s)/protein(s) via UniProtKB accession numbers or protein function keywords. The system is accessible at http://www.proteomicsresource.org/.
has issue date	2007-11-04(xsd:dateTime)
bibo:doi	10.1093/nar/gkm903
bibo:pmid	17984082
has license	cc-by-nc
sha1sum (hex)	c5f1c29433d6c5e4bed3a83ee1c94f003f597ea4
schema:url	https://doi.org/10.1093/nar/gkm903
resource representing a document's title	An emerging cyberinfrastructure for biodefense pathogen and pathogen–host data
has PubMed Central identifier	PMC2239001
has PubMed identifier	17984082
schema:publication	Nucleic Acids Res
resource representing a document's body	covid:c5f1c29433d6c5e4bed3a83ee1c94f003f597ea4#body_text
is schema:about of	named entity 'NMR' named entity 'MASS SPECTROMETRY' named entity 'KEYWORDS' named entity 'ACCESSION NUMBERS' named entity 'EXPERIMENTAL DATA' named entity 'PATHOGENS' named entity 'IN VITRO' named entity 'PROTEIN INTERACTIONS' named entity 'DATABASE' named entity 'PROVIDES' named entity 'ACCESSIBLE' named entity 'PROTEOMICS' named entity 'SYSTEM' named entity 'THERAPEUTICS' named entity 'PROTEIN EXPRESSION' named entity 'INTEGRATED' named entity 'ANALYSIS' named entity 'PATHOGEN PROTEIN' named entity 'PROTEIN ' named entity 'MACROPHAGES' named entity 'EXPERIMENT' named entity 'RESEARCHERS' named entity 'DERIVED' named entity 'HOST' named entity 'CONTEXT' named entity 'X-RAY' named entity 'PUBLICATION' named entity 'GROUP' named entity 'TRANSCRIPTIONAL' named entity 'INTERFACE' named entity 'MOUSE' named entity 'GENE EXPRESSION PROFILES' named entity 'IN VIVO' named entity 'TOXOPLASMA' named entity 'SEVEN' named entity 'DATA' named entity 'TO SUPPORT' named entity 'ACROSS' named entity 'GENE' named entity 'DISSEMINATION' named entity 'ENABLES' named entity 'The' named entity 'NMR' named entity 'UniProtKB' named entity 'Cryptosporidium' named entity 'Research' named entity 'cover' named entity 'ORGANISMS' named entity 'INDIVIDUAL' named entity 'GENERATION' named entity 'HUMAN TISSUE' named entity 'DETERMINED' named entity 'PATHOGEN' named entity 'EXPERIMENTS' named entity 'PROTEIN' named entity 'DIVERSE' named entity 'DATA' named entity '28S' named entity 'GROWING' named entity 'STORAGE' named entity 'VIBRIO' named entity 'PROTEIN STRUCTURES'

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