About: Chemokines and NK cells: Regulators of development, trafficking and functions

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Chemokines and NK cells: Regulators of development, trafficking and functions
Creator	Santoni, Angela Bernardini, Giovanni Gismondi, Angela
Source	Elsevier; Medline; PMC
abstract	NK cells are innate lymphocytes capable of killing malignant or infected cells and to produce a wide array of cytokines and chemokines following activation. Chemokines, play critical roles in the regulation of NK cell tissue distribution in normal conditions as well as their rapid recruitment to the parenchyma of injured organs during inflammation, which is critical for NK cell ability to promote protective responses. In this regard, differences in chemokine receptor expression have been reported on specialized NK cell subsets with distinct effector functions and tissue distribution. Besides their role in the regulation of NK cell trafficking, chemotactic molecules can also affect NK cell effector functions by regulating their priming and their ability to kill and secrete cytokines.
has issue date	2012-07-30(xsd:dateTime)
bibo:doi	10.1016/j.imlet.2012.04.014
bibo:pmid	22698182
has license	no-cc
sha1sum (hex)	c6785919628a7f2e24e5f487f688b5154093897f
schema:url	https://doi.org/10.1016/j.imlet.2012.04.014
resource representing a document's title	Chemokines and NK cells: Regulators of development, trafficking and functions
has PubMed Central identifier	PMC7112821
has PubMed identifier	22698182
schema:publication	Immunol Lett
resource representing a document's body	covid:c6785919628a7f2e24e5f487f688b5154093897f#body_text
is schema:about of	named entity 'CHEMOKINES' named entity 'ACTIVATION' named entity 'CHEMOKINES' named entity 'FOLLOWING' named entity 'NK CELLS' named entity 'REGULATORS' named entity 'FUNCTIONS' named entity 'DEVELOPMENT' named entity 'CAPABLE' named entity 'TRAFFICKING' named entity 'CYTOKINES' named entity 'MALIGNANT' named entity 'INFECTED' named entity 'CELLS' named entity 'ARRAY' named entity 'NK CELLS' named entity 'TO PRODUCE' named entity 'LYMPHOCYTES' named entity 'KILLING' named entity 'S T' named entity 'WIDE' named entity 'array' named entity 'lymphocytes' named entity 'effector cells' named entity 'tissue distribution' named entity 'CD34' named entity 'antigen' named entity 'CCR4' named entity 'CXCL12' named entity 'CD56' named entity 'peripheral blood' named entity 'microenvironments' named entity 'hepatitis' named entity 'chemotactic factors' named entity 'NK cells' named entity 'NK-cell' named entity 'NK cells' named entity 'chemokine receptor' named entity 'NK cell' named entity 'CXCL12' named entity 'GFP' named entity 'NK cells' named entity 'granzymes' named entity 'chemokine receptor' named entity 'granulocyte macrophage colony-stimulating factor' named entity 'CX3CL1' named entity 'cytokine' named entity 'DCs' named entity 'Klebsiella pneumoniae' named entity 'NK cells' named entity 'organ' named entity 'NK cell' named entity 'CXCR2' named entity 'NK cell' named entity 'AMD' named entity 'CXCL10' named entity 'hematopoietic cells' named entity 'CXCL12' named entity 'spleen' named entity 'CD94' named entity 'NK cell' named entity 'NK cells' named entity 'NK cell' named entity 'Secretion' named entity 'stromal cells' named entity 'lymphoid organs' named entity 'antagonist' named entity 'IL-15' named entity 'chemokine receptor' named entity 'chemokine' named entity 'IL-18' named entity 'CD56' named entity 'CD127' named entity 'NK cells' named entity 'medulla' named entity 'high levels' named entity 'CCL19' named entity 'biopsies' named entity 'NK cell'

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