About: Effect of granulocyte colony-stimulating factor (G-CSF) on chemotherapy-induced oral mucositis

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About: Effect of granulocyte colony-stimulating factor (G-CSF) on chemotherapy-induced oral mucositis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Effect of granulocyte colony-stimulating factor (G-CSF) on chemotherapy-induced oral mucositis
Creator	Hisatsugu, Takeharu Iyama, Akihiro Katano, Mitsuo Matsuo, Tatsuya Nakamura, Mitsunari
source	PMC
abstract	In this study, the ability of granulocyte colony-stimulating factor (G-CSF) to treat or prevent chemotherapy-induced oral mucositis in patients with advanced breast cancer was evaluated. A total of 14 patients who received intra-arterial (i.a.) adriamycin (ADM) preoperatively were divided into two groups according to whether or not G-CSF was given. Thus, group A (n=7) was given G-CSF and group B (n=7) was not. G-CSF therapy reduced both the incidence and duration of ADM-induced oral mucositis, and a positive correlation was also seen between the incidence of mucositis and ADM-induced leukopenia (<2,000/mm(3)). Group A was further divided into two subgroups according to whether G-CSF was given after or before the leukopenia had dropped below 2,000/mm(3): group A-1 (n=3) and group A-2 (n=4), respectively. ADM-induced mucositis was observed in two of the three patients in group A-1, but in none of the four patients in group A-2. These results strongly support the idea that G-CSF can effectively treat and prevent ADM-induced oral mucositis.
has issue date	1995-01-01(xsd:dateTime)
bibo:doi	10.1007/bf00311527
bibo:pmid	7543781
has license	no-cc
sha1sum (hex)	c87fb332078d4d4d2d30c389b756c43e88adc1d9
schema:url	https://doi.org/10.1007/bf00311527
resource representing a document's title	Effect of granulocyte colony-stimulating factor (G-CSF) on chemotherapy-induced oral mucositis
has PubMed Central identifier	PMC7101795
has PubMed identifier	7543781
schema:publication	Surg Today
resource representing a document's body	covid:c87fb332078d4d4d2d30c389b756c43e88adc1d9#body_text
is schema:about of	named entity 'support' named entity 'ADM' named entity 'patients' named entity 'Granulocyte' named entity 'Factor' named entity 'FACTOR' named entity 'received' named entity 'subgroups' named entity 'G-CSF' named entity 'group B' named entity 'prevent' named entity 'Thus' named entity 'treat' named entity 'positive correlation' named entity 'growth factor' named entity 'mucositis' named entity 'mucositis' named entity 'leukocytes' named entity 'serum level' named entity 'adriamycin' named entity 'oral ulceration' named entity 'Mucositis' named entity 'adult respiratory distress syndrome' named entity 'herpes virus' named entity 'inflammatory breast cancer' named entity 'neutrophil' named entity 'chemotherapy-induced' named entity 'oral mucositis' named entity 'G-CSF' named entity 'leukopenia' named entity 'Japan' named entity '5-FU' named entity 'mucositis' named entity 'toxicity' named entity 'hematopoietic' named entity 'oral mucosa' named entity 'chemotherapy-induced' named entity 'mucosal barriers' named entity 'clinical trials' named entity 'mucositis' named entity 'GM-CSF' named entity 'neutrophils' named entity 'G-CSF' named entity 'neutropenia' named entity 'peripheral blood' named entity 'neutropenia' named entity 'Chemotherapeutic agents' named entity 'adriamycin' named entity 'advanced breast cancer' named entity 'combination chemotherapy' named entity 'leukocyte count' named entity 'cyclic neutropenia' named entity 'leukocyte' named entity 'mucositis' named entity 'ARDS' named entity 'breast cancer' named entity 'granulocyte-macrophage colony-stimulating factor' named entity '5-fluorouracil' named entity 'hematopoietic growth factor' named entity '8 days' named entity 'chemotherapy-induced' named entity 'Mucositis' named entity 'mucositis' named entity '5-FU' named entity 'GM-CSF' named entity 'mucositis' named entity 'breast cancer' named entity 'Oral mucositis' named entity 'neutropenia' named entity 'G-CSF' named entity 'fever' named entity 'leukopenia' named entity 'Chinese hamster ovary cells' named entity 'doxorubicin' named entity 'G-CSF' named entity 'oral mucosal' named entity 'toxicity'

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