About: Anti‐poliovirus activity of Baccharis dracunculifolia and propolis by cell viability determination and real‐time PCR

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Anti‐poliovirus activity of Baccharis dracunculifolia and propolis by cell viability determination and real‐time PCR Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Anti‐poliovirus activity of Baccharis dracunculifolia and propolis by cell viability determination and real‐time PCR
Creator	Bastos, J Bú Falo, M Candeias, J De Sousa, J Figueiredo, A Sforcin, J
source	Medline; PMC
abstract	Aims: The aim of this work was to evaluate the antiviral activities of Baccharis dracunculifolia (extract and essential oil), propolis and some isolated compounds (caffeic and cinnamic acids) against poliovirus type 1 (PV1) replication in HEp‐2 cells. Method: Three different protocols (pre‐, simultaneous and post‐treatments) were used to verify the effect of addition time of the variables on PV1 replication by crystal violet method and relative viral RNA quantification by real‐time PCR for analysing in which step of virus replication the variables could interfere. Conclusions: Data revealed that the B. dracunculifolia showed the best antiviral activity percentage in the simultaneous treatment, as well as lower relative viral quantification by real‐time PCR. Variables might block partially the viral entry within cells, affect the steps of viral cycle replication into cells, or lead to RNA degradation before the virus entry into cells or after their release to the supernatant. Significance and Impact of the Study: Baccharis dracunculifolia is the most important botanical source of the south‐eastern Brazilian propolis, and its potential for the development of new phytotherapeutic medicines has been investigated. Propolis is commonly used for its antimicrobial and immunomodulatory activities. Nevertheless, B. dracunculifolia and propolis effects on PV1 have not been investigated yet.
has issue date	2009-04-21(xsd:dateTime)
bibo:doi	10.1111/j.1365-2672.2009.04354.x
bibo:pmid	19457040
has license	no-cc
sha1sum (hex)	cb44c7a5195dcd6757837c9b9f15ab21b72628d7
schema:url	https://doi.org/10.1111/j.1365-2672.2009.04354.x
resource representing a document's title	Anti‐poliovirus activity of Baccharis dracunculifolia and propolis by cell viability determination and real‐time PCR
has PubMed Central identifier	PMC7197736
has PubMed identifier	19457040
schema:publication	J Appl Microbiol
resource representing a document's body	covid:cb44c7a5195dcd6757837c9b9f15ab21b72628d7#body_text
is schema:about of	named entity 'cell viability' named entity 'cinnamic acids' named entity 'caffeic' named entity 'HEp-2' named entity 'positive control' named entity 'GeneBank' named entity 'humulene' named entity 'solvent' named entity 'antiviral' named entity 'HEp-2' named entity 'Bankova' named entity 'HEp-2' named entity 'prenylated' named entity 'p-coumaric acid' named entity 'Baccharis' named entity 'Baccharis' named entity 'sulphate' named entity 'Brazil' named entity 'Baccharis' named entity 'viruses' named entity 'liquid nitrogen' named entity 'p-coumaric acid' named entity 'propolis' named entity 'RNA' named entity 'viral cycle' named entity 'SDS' named entity 'viral RNA' named entity 'B. dracunculifolia' named entity 'propolis' named entity 'PCR' named entity 'propolis' named entity 'propolis' named entity 'antiviral' named entity 'Morris Plains' named entity 'propolis' named entity 'positive controls' named entity 'propolis' named entity 'Baccharis dracunculifolia' named entity 'nucleic acids' named entity 'virus' named entity 'B. dracunculifolia' named entity 'virus' named entity 'caffeic' named entity 'viral RNA' named entity 'propolis' named entity 'Baccharis' named entity 'cell cultures' named entity 'RNA' named entity 'propolis' named entity 'essential oil' named entity 'essential oil' named entity 'propolis' named entity 'sensitivity and specificity' named entity 'essential oil' named entity 'HEp-2' named entity 'Erlenmeyer flasks' named entity 'essential oil' named entity 'l-glutamine' named entity 'propolis' named entity 'gastrointestinal diseases' named entity 'B. dracunculifolia' named entity 'caffeic' named entity 'propolis' named entity 'HSV' named entity 'antiviral agents' named entity 'nmol' named entity 'Baccharis' named entity 'caffeic acid' named entity 'lysates' named entity 'limonene' named entity 'virus' named entity 'essential oil' named entity 'supernatant' named entity 'infection' named entity 'RNA' named entity 'RNA extraction'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software