About: Effect of experimentally-induced villus atrophy on adhesion of K88ac-positive Escherichia coli in just-weaned piglets

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About: Effect of experimentally-induced villus atrophy on adhesion of K88ac-positive Escherichia coli in just-weaned piglets Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Effect of experimentally-induced villus atrophy on adhesion of K88ac-positive Escherichia coli in just-weaned piglets
Creator	Cox, E Hoorens, J Cools, V Houvenaghel, A Thoonen, H
Source	PMC
abstract	Three- to four-week-old, just-weaned piglets were infected with transmissible gastroenteritis (TGE) virus and the next day with K88ac(+) enterotoxigenic Escherichia coli (ETEC). Histological examination of caudal jejunum and ileum of piglets killed 2–3 days after virus challenge (1–2 days after ETEC infection) revealed severe villus atrophy especially in the jejunum compared with controls (P<0.05). Four-5 days after TGE virus infection villus length increased and after 7 days it was near normal. Villi scraped from jejunal and ileal mucosa of the piglets were incubated in vitro with K88ac(+)E. coli and the number of bacteria adhering to 250 μm villus brush border was counted. Attachment of bacteria to villi of piglets killed 2–3 days after TGE virus infection was significantly decreased in comparison with adhesion to villi of non-infected piglets or of piglets killed 7 days after the virus infection. Correlation between in vitro adhesion and villus height was 0.6649 (P<0.001). The results suggest that the experimentally-induced villus atrophy was attended with a temporarily diminished susceptibility of villus enterocytes to adhesion of K88ac(+)E. coli.
has issue date	2002-11-12(xsd:dateTime)
bibo:doi	10.1016/0378-1135(88)90007-7
bibo:pmid	3051650
has license	no-cc
sha1sum (hex)	d259cfcaf0924b7ed7e8e332c4087a4768c99782
schema:url	https://doi.org/10.1016/0378-1135%2888%2990007-7
resource representing a document's title	Effect of experimentally-induced villus atrophy on adhesion of K88ac-positive Escherichia coli in just-weaned piglets
has PubMed Central identifier	PMC7117471
has PubMed identifier	3051650
schema:publication	Vet Microbiol
resource representing a document's body	covid:d259cfcaf0924b7ed7e8e332c4087a4768c99782#body_text
is schema:about of	named entity 'INDUCED' named entity 'length' named entity 'normal' named entity 'infection' named entity 'virus' named entity 'jejunal' named entity 'virus' named entity 'ENTEROCYTES' named entity 'VIRUS INFECTION' named entity '250' named entity 'JEJUNUM' named entity '2-3 DAYS' named entity 'HEIGHT' named entity '1-2 DAYS' named entity 'ATTACHMENT' named entity 'CORRELATION' named entity 'ILEUM' named entity 'LENGTH' named entity 'TGE' named entity '0.05' named entity 'VIRUS' named entity 'NORMAL' named entity 'DAY' named entity 'POSITIVE ESCHERICHIA COLI' named entity 'RESULTS' named entity 'COX' named entity 'JUST' named entity 'REVEALED' named entity 'DAYS' named entity 'CHALLENGE' named entity 'BACTERIA ' named entity 'KILLED' named entity 'ADHERING' named entity 'VILLUS' named entity 'DIMINISHED' named entity 'CAUDAL' named entity 'WEEK' named entity 'GASTROENTERITIS' named entity 'ATROPHY' named entity 'HISTOLOGICAL EXAMINATION' named entity 'EFFECT' named entity 'NEAR' covid:arg/d259cfcaf0924b7ed7e8e332c4087a4768c99782 named entity 'COMPARED' named entity 'ADHESION' named entity 'SUGGEST' named entity 'VET' named entity 'NON-INFECTED' named entity 'WEANED' named entity 'ENTEROTOXIGENIC ESCHERICHIA COLI' named entity 'JUST' named entity 'VILLUS' named entity 'WEANED' named entity 'EFFECT' named entity 'POSITIVE ESCHERICHIA COLI' named entity 'ILEAL MUCOSA' named entity 'OLD' named entity 'SEVERE' named entity 'NUMBER OF' named entity 'H.%' named entity 'INFECTION' named entity 'INDUCED' named entity 'INCREASED' named entity 'INFECTED' named entity '6649' named entity 'E. COLI' named entity 'DECREASED' named entity 'BRUSH BORDER' named entity 'INCUBATED' named entity 'IN VITRO' named entity '28P' named entity 'JEJUNAL' named entity 'SUSCEPTIBILITY' named entity 'SCRAPED' named entity 'COMPARISON' named entity 'ADHESION' named entity 'ATROPHY'

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