About: Pathobiology of Avian avulavirus 1: special focus on waterfowl

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Pathobiology of Avian avulavirus 1: special focus on waterfowl
Creator	Ding, Chan Meng, Chunchun Sun, Yingjie Umar, Sajid Munir, Muhammad Mahrose, Khalid Rehman, Zaib
source	PMC
abstract	Avian avulaviruses serotype 1 (abbreviated as APMV-1 for the historical name avian paramyxovirus 1) are capable of infecting a wide spectrum of avian species with variable clinical symptoms and outcomes. Ease of transmission has allowed the virus to spread worldwide with varying degrees of virulence depending upon the virus strain and host species. The emergence of new virulent genotypes from global epizootics, and the year-to-year genomic changes in low and high virulence APMV-1 imply that distinct genotypes of APMV-1 are simultaneously evolving at different geographic locations across the globe. This vast genomic diversity may be favoured by large variety of avian species susceptibility to APMV-1 infection, and by the availability of highly mobile wild birds. It has long been considered that waterfowls are not sensitive to APMV-1 and are unable to show any clinical signs, however, outbreaks from the 90′s contradict these concepts. The APMV-1 isolates are increasingly reported from the waterfowl. Waterfowl have strong innate immune responses, which minimize the impact of virus infection, however, are unable to prevent the viral shedding. Numerous APMV-1 are carried by domestic waterfowl intermingling with terrestrial poultry. Therefore, commercial ducks and geese should be vaccinated against APMV-1 to minimize the virus shedding and for the prevention the transmission. Genetic diversity within APMV-1 demonstrates the need for continual monitoring of viral evolution and periodic updates of vaccine seed-strains to achieve efficient control and eradication of APMV-1 in waterfowls. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13567-018-0587-x) contains supplementary material, which is available to authorized users.
has issue date	2018-09-19(xsd:dateTime)
bibo:doi	10.1186/s13567-018-0587-x
bibo:pmid	30231933
has license	cc-by
sha1sum (hex)	d8ec38752ec638efa9b55dffa8d0277ce889c976
schema:url	https://doi.org/10.1186/s13567-018-0587-x
resource representing a document's title	Pathobiology of Avian avulavirus 1: special focus on waterfowl
has PubMed Central identifier	PMC6148804
has PubMed identifier	30231933
schema:publication	Vet Res
resource representing a document's body	covid:d8ec38752ec638efa9b55dffa8d0277ce889c976#body_text
is schema:about of	named entity 'global' named entity 'virus' named entity 'transmission' named entity 'Waterfowl' named entity 'host' named entity 'PATHOBIOLOGY' named entity 'HIGH' named entity 'COMMERCIAL' named entity 'AVIAN' named entity 'OUTCOMES' named entity 'LARGE' named entity 'SEROTYPE' named entity 'ERADICATION' named entity 'ISOLATES' named entity 'PREVENTION' named entity 'IMPACT' named entity 'MONITORING' named entity 'B2S' named entity 'TRANSMISSION' named entity 'VIRUS' named entity '80%' named entity 'VIRUS INFECTION' named entity 'VACCINATED' named entity 'EASE' named entity 'VACCINE' named entity 'SPECTRUM' named entity 'LOW' named entity 'GENOMIC' named entity 'SUSCEPTIBILITY' named entity 'EPIZOOTICS' named entity 'VARYING' named entity 'SPREAD' named entity 'INFECTION' named entity 'CONSIDERED' named entity 'DEGREES' named entity 'ALLOWED' named entity 'CARRIED' named entity 'VIRUS SHEDDING' named entity 'SIMULTANEOUSLY' named entity 'CAPABLE' named entity 'CONTINUAL' named entity 'AVAILABILITY OF' named entity 'HOST SPECIES' named entity 'GLOBE' named entity 'CONCEPTS' named entity 'DIVERSITY' named entity 'WORLDWIDE' named entity 'VIRULENCE' named entity 'DOMESTIC' named entity 'STRAINS' named entity 'NEW' named entity 'AVIAN PARAMYXOVIRUS 1' named entity 'STRONG' named entity 'POULTRY' named entity 'GLOBAL' named entity 'ACROSS' named entity 'AVIAN AVULAVIRUS 1' named entity 'VIRAL EVOLUTION' named entity 'EVOLVING' named entity 'BIRDS' named entity 'VIRULENT' named entity 'CLINICAL SIGNS' named entity 'INFECTING' named entity 'NUMEROUS' named entity 'EMERGENCE' named entity 'VIRAL SHEDDING' named entity 'SEED' named entity 'CONTROL' named entity 'DIFFERENT' named entity 'WATERFOWL' named entity 'GEOGRAPHIC LOCATIONS' named entity 'VARIETY' named entity 'DISTINCT' named entity 'SPECIAL' named entity 'FOCUS'

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