About: To Go or Stay: The Development, Benefit, and Detriment of Tissue-Resident Memory CD8 T Cells during Central Nervous System Viral Infections

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: To Go or Stay: The Development, Benefit, and Detriment of Tissue-Resident Memory CD8 T Cells during Central Nervous System Viral Infections Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	To Go or Stay: The Development, Benefit, and Detriment of Tissue-Resident Memory CD8 T Cells during Central Nervous System Viral Infections
Creator	Lukacher, Aron Mockus, Taryn Ren, Heather
Source	Medline; PMC
abstract	CD8 T cells coordinate immune defenses against viral infections of the central nervous system (CNS). Virus-specific CD8 T cells infiltrate the CNS and differentiate into brain-resident memory CD8 T cells (CD8 bT(RM)). CD8 bT(RM) are characterized by a lack of recirculation and expression of phenotypes and transcriptomes distinct from other CD8 T cell memory subsets. CD8 bT(RM) have been shown to provide durable, autonomous protection against viral reinfection and the resurgence of latent viral infections. CD8 T cells have also been implicated in the development of neural damage following viral infection, which demonstrates that the infiltration of CD8 T cells into the brain can also be pathogenic. In this review, we will explore the residency and maintenance requirements for CD8 bT(RM) and discuss their roles in controlling viral infections of the brain.
has issue date	2019-09-11(xsd:dateTime)
bibo:doi	10.3390/v11090842
bibo:pmid	31514273
has license	cc-by
sha1sum (hex)	dcbe31a68ac67d38ccdae0615ebabd8461bd7095
schema:url	https://doi.org/10.3390/v11090842
resource representing a document's title	To Go or Stay: The Development, Benefit, and Detriment of Tissue-Resident Memory CD8 T Cells during Central Nervous System Viral Infections
has PubMed Central identifier	PMC6784233
has PubMed identifier	31514273
schema:publication	Viruses
resource representing a document's body	covid:dcbe31a68ac67d38ccdae0615ebabd8461bd7095#body_text
is schema:about of	named entity 'MEMORY' named entity 'expression' named entity 'damage' named entity 'infiltration' named entity 'Infections' named entity 'Viral' named entity 'RESIDENT' covid:arg/dcbe31a68ac67d38ccdae0615ebabd8461bd7095 named entity 'RESIDENCY' named entity 'INFILTRATE' named entity 'MEMORY' named entity 'DISTINCT FROM' named entity 'LACK' named entity 'PATHOGENIC' named entity 'VIRAL INFECTIONS' named entity 'VIRAL INFECTION' named entity 'PHENOTYPES' named entity 'IMMUNE' named entity 'DEVELOPMENT' named entity 'CD8' named entity 'DEVELOPMENT' named entity 'RECIRCULATION' named entity 'SPECIFIC' named entity 'BRAIN' named entity 'T CELL MEMORY' named entity 'CD8' named entity 'BENEFIT' named entity 'TO PROVIDE' named entity 'AUTONOMOUS' named entity 'VIRUS' named entity 'DIFFERENTIATE' named entity 'REQUIREMENTS' named entity 'NEURAL DAMAGE' named entity 'RESIDENT' named entity 'CONTROLLING' named entity 'FOLLOWING' named entity 'T CELLS' named entity 'PROTECTION' named entity 'RESURGENCE' named entity 'REVIEW' named entity 'VIRAL' named entity 'DISCUSS' named entity 'CNS' named entity 'LATENT' named entity 'T CELLS' named entity 'TISSUE' named entity 'REINFECTION' named entity 'ROLES' named entity 'EXPRESSION' named entity 'INFILTRATION' named entity 'COORDINATE' named entity 'CHARACTERIZED' named entity 'VIRAL INFECTIONS' named entity 'CENTRAL NERVOUS SYSTEM' named entity 'HAVE' named entity 'VIRAL INFECTIONS OF THE CENTRAL NERVOUS SYSTEM' named entity 'MAINTENANCE' named entity 'THEIR' named entity 'development' named entity 'memory' named entity 'viral' named entity 'T cell' named entity 'transcriptomes' named entity 'neural' named entity 'CD8' named entity 'CNS' named entity 'viral infection' named entity 'CNS' named entity 'latent viral infections' named entity 'CD8' named entity 'CD8 T cells' named entity 'CD8' named entity 'T cells' named entity 'lymphoid tissues' named entity 'immunopathology' named entity 'PD-L1' named entity 'antiviral' named entity 'Toxoplasma gondii' named entity 'SINV'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software