About: The Effects of Allium Sativum on Immunity within the Scope of COVID-19 Infection

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The Effects of Allium Sativum on Immunity within the Scope of COVID-19 Infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The Effects of Allium Sativum on Immunity within the Scope of COVID-19 Infection
Creator	Donma, Mustafa Donma, Orkide Metin Donma, Mustafa Orkide Donma,
Source	Elsevier; Medline; PMC
abstract	The severity of coronavirus disease 2019 (COVID‐19) infection is quite variable and the manifestations varies from asymptomatic disease to severe acute respiratory infection. Fever, dry cough, dyspnea, myalgia, fatigue, loss of appetite, olfactory and gustatory dysfunctions are the most prevalent general symptoms. Decreased immune system cells such as suppressed regulatory T cells, cytotoxic and helper T cells, natural killer cells, monocytes/macrophages and increased proinflammatory cytokines are the characteristic features. Compounds derived from Allium sativum (garlic) have the potential to decrease the expression of proinflammatory cytokines and to reverse the immunological abnormalities to more acceptable levels. Allium sativum is suggested as a beneficial preventive measure before being infected with SARS‐CoV‐2 virus. Allium sativum is a functional food well-known for its immunomodulatory, antimicrobial, antiinflammatory, antimutagenic, antitumor properties. Its antiviral efficiency was also demonstrated. Some constituents of this plant were found to be active against protozoan parasites. Within this context, it appears to reverse most immune system dysfunctions observed in patients with COVID-19 infection. The relations among immune system parameters, leptin, leptin receptor, adenosin mono phosphate-activated protein kinase, peroxisome proliferator activated receptor-gamma have also been interpreted. Leptin’s role in boosting proinflammatory cytokines and in appetite decreasing suggest the possible beneficial effect of decreasing the concentration of this proinflammatory adipose tissue hormone in relieving some symptoms detected during COVID-19 infection. In conclusion, Allium sativum may be an acceptable preventive measure against COVID-19 infection to boost immune system cells and to repress the production and secretion of proinflammatory cytokines as well as an adipose tissue derived hormone leptin having the proinflammatory nature.
has issue date	2020-06-02(xsd:dateTime)
bibo:doi	10.1016/j.mehy.2020.109934
bibo:pmid	32512493
has license	no-cc
sha1sum (hex)	dde0f97eec4efe5e5c91f4c7a84a87c754a135ef
schema:url	https://doi.org/10.1016/j.mehy.2020.109934
resource representing a document's title	The Effects of Allium Sativum on Immunity within the Scope of COVID-19 Infection
has PubMed Central identifier	PMC7265825
has PubMed identifier	32512493
schema:publication	Med Hypotheses
resource representing a document's body	covid:dde0f97eec4efe5e5c91f4c7a84a87c754a135ef#body_text
is schema:about of	named entity 'Allium sativum' named entity 'dyspnea' named entity 'symptoms' named entity 'VIRUS' named entity 'MONOCYTES' named entity 'CORONAVIRUS DISEASE 2019' named entity 'PREVALENT' named entity 'MANIFESTATIONS' named entity 'SARS-COV-2' named entity 'EXPRESSION' covid:arg/dde0f97eec4efe5e5c91f4c7a84a87c754a135ef named entity 'acceptable' named entity 'immunological' named entity 'Peroxisome proliferator' named entity 'Leptin' named entity 'interleukin-2' named entity 'leptin' named entity 'protein' named entity 'Immuno-compromised' named entity 'LepR' named entity 'infection' named entity 'peroxisome proliferator' named entity 'serum' named entity 'CD4+' named entity 'macrophages' named entity 'IFN-γ' named entity 'obesity epidemic' named entity 'metabolic syndrome' named entity 'IFN-γ' named entity 'viral infection' named entity 'phosphorylation' named entity 'proinflammatory cytokines' named entity 'acetyl CoA carboxylase' named entity 'leptin receptor' named entity 'obesity' named entity 'garlic' named entity 'ABG' named entity 'hemoglobin' named entity 'Plasmodium' named entity '45 days' named entity 'helper T cells' named entity 'Coronavirus disease 2019' named entity 'tumor size' named entity 'NK cells' named entity 'alliin' named entity 'hormonal' named entity 'infection' named entity 'SARS-CoV' named entity 'CD8+ T cell' named entity 'Garlic' named entity 'herbal medicine' named entity 'CMV' named entity 'adipose' named entity 'eosinophils' named entity 'dry cough' named entity 'proinflammatory cytokines' named entity 'loss of appetite' named entity 'SARS-CoV-2 virus' named entity 'garlic' named entity 'natural killer cells' named entity 'macrophages' named entity 'asymptomatic' named entity 'immunological' named entity 'proinflammatory cytokines' named entity 'Fever' named entity 'Sativum' named entity 'COVID-19' named entity 'olfactory' named entity 'CD8+' named entity 'phosphorylates' named entity 'lymphocytes' named entity 'immune-compromised' named entity 'garlic' named entity 'leptin receptor' named entity 'COVID-19' named entity 'cardiovascular disorders' named entity 'obese people' named entity 'IL-6'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software