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About:
Prediction of Postoperative Mortality in Patients with Organ Failure After Gastric Cancer Surgery
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wasabi.inria.fr
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Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Prediction of Postoperative Mortality in Patients with Organ Failure After Gastric Cancer Surgery
Creator
Kim, Han
Felix Berlth, •
Huh, Yeon-Ju
Kong, Seong-Ho
Lee, Hyuk-Joon
Lee, Kyung-Goo
Oh, Seung-Young
Park, Ji-Ho
Park, Shin-Hoo
Son, Young-Gil
Suh, Yun-Suhk
Tae, •
Yang, Han-Kwang
Yang, Jun-Young
source
PMC
abstract
BACKGROUND: Scarce data are available on the characteristics of postoperative organ failure (POF) and mortality after gastrectomy. We aimed to describe the causes of organ failure and mortality related to gastrectomy for gastric cancer and to identify patients with POF who are at a risk of failure to rescue (FTR). METHODS: The study examined patients with POF or in-hospital mortality in Seoul National University Hospital between 2005 and 2014. We identified patients at a high risk of FTR by analyzing laboratory findings, complication data, intensive care unit records, and risk scoring including Acute Physiology and Chronic Health Evaluation (APACHE) IV, Sequential Organ Failure Assessment (SOFA) score, and Simplified Acute Physiology Score (SAPS) 3 at ICU admission. RESULTS: Among the 7304 patients who underwent gastrectomy, 80 (1.1%) were identified with Clavien–Dindo classification (CDC) grade ≥ IVa. The numbers of patients with CDC grade IVa, IVb, and V were 48 (0.66%), 11 (0.15%), and 21 (0.29%), respectively. Pulmonary failure (43.8%), surgical site complication (27.5%), and cardiac failure (13.8%) were the most common causes of POF and mortality. Cancer progression (100%) and cardiac events (45.5%) showed high FTR rates. In univariate analysis, acidosis, hypoalbuminemia, SOFA, APACHE IV, and SAPS 3 were identified as risk factors for FTR (P < 0.05). Finally, SAPS 3 was identified as an independent predictive factor for FTR. CONCLUSIONS: Cancer progression and acute cardiac failure were the most lethal causes of FTR. SAPS 3 is an independent predictor of FTR among POF patients after gastrectomy.
has issue date
2020-01-28
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bibo:doi
10.1007/s00268-020-05382-9
bibo:pmid
31993720
has license
no-cc
sha1sum (hex)
dde62ae47d96f566e2bb316f9d73b494e904c072
schema:url
https://doi.org/10.1007/s00268-020-05382-9
resource representing a document's title
Prediction of Postoperative Mortality in Patients with Organ Failure After Gastric Cancer Surgery
has PubMed Central identifier
PMC7223481
has PubMed identifier
31993720
schema:publication
World J Surg
resource representing a document's body
covid:dde62ae47d96f566e2bb316f9d73b494e904c072#body_text
is
schema:about
of
named entity 'Evaluation'
named entity '2005'
named entity 'independent'
named entity 'POF'
named entity 'Health'
named entity 'risk'
named entity 'FTR'
named entity 'Acute'
named entity 'POF'
named entity 'data'
named entity 'Organ'
named entity 'Failure'
named entity 'SAPS'
named entity 'records'
named entity 'risk factors'
named entity 'Chronic'
named entity 'univariate analysis'
named entity 'patients'
named entity 'gastrectomy'
named entity 'acute'
named entity 'Cancer'
named entity 'ICU'
named entity 'surgical site'
named entity 'hepatic'
named entity 'ventilator'
named entity 'pulmonary failure'
named entity 'organ failure'
named entity 'organ failure'
named entity 'Charlson comorbidity index'
named entity 'ICU'
named entity 'ICU'
named entity 'comorbidity'
named entity 'myocardial infarction'
named entity 'jejunostomy'
named entity 'gastrectomy'
named entity 'ICU'
named entity 'FTR'
named entity 'ICU'
named entity 'CDC'
named entity 'surgical site'
named entity 'ventilator'
named entity 'organ failure'
named entity 'ascites'
named entity 'ICU'
named entity 'inclusion and exclusion criteria'
named entity 'hypoalbuminemia'
named entity 'homeostasis'
named entity 'heart rate'
named entity 'congestive heart failure'
named entity 'anemia'
named entity 'ICU'
named entity 'diabetes mellitus'
named entity 'randomized controlled trials'
named entity 'medical conditions'
named entity 'organ failure'
named entity 'surgical techniques'
named entity 'organ failure'
named entity 'organ failure'
named entity 'organ failure'
named entity 'organ failure'
named entity 'Chronic Health'
named entity 'Organ failure'
named entity 'mortality rate'
named entity 'FTR'
named entity 'comorbidities'
named entity 'abscess'
named entity 'cholecystectomy'
named entity 'platelets'
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