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About:
Identification of GBV-D, a Novel GB-like Flavivirus from Old World Frugivorous Bats (Pteropus giganteus) in Bangladesh
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Identification of GBV-D, a Novel GB-like Flavivirus from Old World Frugivorous Bats (Pteropus giganteus) in Bangladesh
Creator
Luby, Stephen
Daszak, Peter
Briese, Thomas
Conlan, Sean
Quan, Phenix-Lan
Jabado, Omar
Egholm, Michael
Street, Craig
Epstein, Jonathan
Hossain, M
Hutchison, Stephen
Khan, Shahneaz
Lipkin, W
Verdugo, Dawn
source
Medline; PMC
abstract
Bats are reservoirs for a wide range of zoonotic agents including lyssa-, henipah-, SARS-like corona-, Marburg-, Ebola-, and astroviruses. In an effort to survey for the presence of other infectious agents, known and unknown, we screened sera from 16 Pteropus giganteus bats from Faridpur, Bangladesh, using high-throughput pyrosequencing. Sequence analyses indicated the presence of a previously undescribed virus that has approximately 50% identity at the amino acid level to GB virus A and C (GBV-A and -C). Viral nucleic acid was present in 5 of 98 sera (5%) from a single colony of free-ranging bats. Infection was not associated with evidence of hepatitis or hepatic dysfunction. Phylogenetic analysis indicates that this first GBV-like flavivirus reported in bats constitutes a distinct species within the Flaviviridae family and is ancestral to the GBV-A and -C virus clades.
has issue date
2010-07-01
(
xsd:dateTime
)
bibo:doi
10.1371/journal.ppat.1000972
bibo:pmid
20617167
has license
cc-by
sha1sum (hex)
de294d87c6450898768c48ddea59cf9320df5e7e
schema:url
https://doi.org/10.1371/journal.ppat.1000972
resource representing a document's title
Identification of GBV-D, a Novel GB-like Flavivirus from Old World Frugivorous Bats (Pteropus giganteus) in Bangladesh
has PubMed Central identifier
PMC2895649
has PubMed identifier
20617167
schema:publication
PLoS Pathog
resource representing a document's body
covid:de294d87c6450898768c48ddea59cf9320df5e7e#body_text
is
schema:about
of
named entity 'pyrosequencing'
named entity 'hepatic dysfunction'
named entity 'screened'
named entity 'survey'
named entity 'presence'
named entity 'Novel'
named entity 'clades'
named entity 'Viral'
named entity 'high-throughput'
named entity 'corona'
named entity 'hepatic dysfunction'
named entity 'high-throughput'
named entity 'Faridpur, Bangladesh'
named entity 'pyrosequencing'
named entity 'clades'
named entity 'virus'
named entity 'hepatitis'
named entity 'GBV'
named entity 'Sequence analyses'
named entity 'Ebola'
named entity 'GBV'
named entity 'Pteropus giganteus'
named entity 'Marburg'
named entity 'GBV'
named entity 'NS5B'
named entity 'habitat'
named entity 'bat'
named entity 'Austin, TX'
named entity 'pfam'
named entity 'Japanese encephalitis'
named entity 'Invitrogen'
named entity 'Bangladesh'
named entity 'Nipah virus'
named entity 'GBV-D'
named entity 'nucleic acids'
named entity 'viruses'
named entity 'bat'
named entity 'phosphorylation'
named entity 'cis-acting'
named entity 'flaviviruses'
named entity 'genome sequence'
named entity 'saliva'
named entity 'London'
named entity 'bat'
named entity 'mammals'
named entity 'Hilden'
named entity 'Invitrogen'
named entity 'Geneious'
named entity 'autocatalytic'
named entity 'lactate dehydrogenase'
named entity 'zoonotic transmission'
named entity 'viruses'
named entity 'Bangaldesh'
named entity 'BLASTN'
named entity 'bat'
named entity 'indel'
named entity 'serine protease'
named entity 'Adelphia'
named entity 'infectious agents'
named entity 'microbial'
named entity 'lactate dehydrogenase'
named entity 'GBV-D'
named entity 'nucleic acid'
named entity 'infection'
named entity 'RNA'
named entity 'homology'
named entity 'saliva'
named entity 'helicase'
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