About: HCV and HEV: two players in an Egyptian village, a study of prevalence, incidence, and co-infection

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About: HCV and HEV: two players in an Egyptian village, a study of prevalence, incidence, and co-infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	HCV and HEV: two players in an Egyptian village, a study of prevalence, incidence, and co-infection
Creator	Kabbash, Ibrahim Abd-Elsalam, Sherief Abo-Ali, Lobna Abo-Elazm, Abdel-Raouf Atia, Sherief Elhendawy, Mohammed Esmat, Gamal Ferial El-Kalla, & Hagras, Maha Kobtan, Abdelrahman Mansour, Loai
Source	PMC
abstract	The highest recorded hepatitis C virus (HCV) prevalence worldwide is in Egypt. A high prevalence of hepatitis E virus (HEV) in chronic liver disease has been reported. The aim of this study was to study prevalence, incidence, and outcome of HCV infection in an Egyptian Nile Delta village and the relation between HEV infection and HCV-related chronic hepatic affection. This prospective cohort study included 2085 Nagreej village residents. Mass HCV screening was conducted and testing for HEV antibodies among HCV-infected patients performed. The annual incidence of HCV was recorded. Five hundred five (24.22%) of the tested villagers were positive for HCV RNA. Prevalence escalated with age and male sex. The main recorded risk factors were a history of surgery, dental procedures, hospitalization, blood transfusion, and antischistosomal treatment. HEV IgG antibody was positive in 71.4% of individuals with chronic HCV and 96.1% with advanced liver disease (cirrhosis ± hepatocellular carcinoma (HCC)). After 1 year, 29 of the 1390 HCV Ab negative villagers had a positive HCV PCR, placing an annual incidence of new HCV infections at 2.09%. The Egyptian HCV prevalence remains high with infection particularly among the elderly. The annual incidence in a small Nile Delta village is 2.086%. HCV-HEV co-infection may lead to a worse prognosis among Egyptians with chronic liver disease. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11356-020-09591-6) contains supplementary material, which is available to authorized users.
has issue date	2020-06-12(xsd:dateTime)
bibo:doi	10.1007/s11356-020-09591-6
has license	no-cc
sha1sum (hex)	e10fa29a5dbae8631d370096563316945b5eb47b
schema:url	https://doi.org/10.1007/s11356-020-09591-6
resource representing a document's title	HCV and HEV: two players in an Egyptian village, a study of prevalence, incidence, and co-infection
has PubMed Central identifier	PMC7292573
schema:publication	Environ Sci Pollut Res Int
resource representing a document's body	covid:e10fa29a5dbae8631d370096563316945b5eb47b#body_text
is schema:about of	named entity 'village' named entity 'PCR' named entity 'infection' named entity 'HCV' named entity 'high' named entity 'infection' named entity 'chronic liver disease' named entity 'co-infection' named entity 'virus' named entity 'positive' named entity 'incidence' named entity 'elderly' named entity 'performed' named entity 'affection' named entity 'infection' named entity 'HCV' named entity 'sex' named entity 'liver disease' named entity 'risk factors' named entity 'surgery' named entity 'residents' named entity 'chronic' named entity 'tested' named entity 'screening' named entity 'Egypt' named entity 'dental procedures' named entity 'HEV' named entity 'chronic liver disease' named entity 'Nile Delta' named entity 'HEV' named entity 'HCV' named entity 'HCV' named entity 'prospective cohort study' named entity 'HCV' named entity 'blood transfusion' named entity 'HEV' named entity 'chronic liver disease' named entity 'advanced liver disease' named entity 'HCV' named entity 'village' named entity 'Egyptian' named entity 'antischistosomal' named entity 'insulin resistance' named entity 'surgical operations' named entity 'infection' named entity 'transfusion' named entity 'infection' named entity 'HCV' named entity 'HEV' named entity 'infection' named entity 'parenteral therapy' named entity 'incidence rate' named entity 'HCV' named entity 'sample size' named entity 'HCV' named entity 'HCV' named entity 'malignancy' named entity 'HCV' named entity 'HEV' named entity 'IgM' named entity 'HCV' named entity 'HCV' named entity 'Nile Delta' named entity 'chronic liver disease' named entity 'cirrhosis' named entity 'mucosal' named entity 'atherosclerotic plaques' named entity 'sequelae' named entity 'RNA' named entity 'logistic regression' named entity 'HCV' named entity 'HEV' named entity 'antibodies'

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