About: Associations of Loneliness and Social Isolation with Healthspan and Lifespan in the US Health and Retirement Study

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About: Associations of Loneliness and Social Isolation with Healthspan and Lifespan in the US Health and Retirement Study Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Associations of Loneliness and Social Isolation with Healthspan and Lifespan in the US Health and Retirement Study
Creator	Bw, Domingue Cl, Crowe Dw, Belsky Km, Keyes Kwon, D
Source	MedRxiv
abstract	Background. Loneliness and social isolation are emerging public health challenges for aging populations. Methods. We followed N=11,305 US Health and Retirement Study (HRS) participants aged 50-95 from 2006-2014 to measure persistence of exposure to loneliness and social isolation. We tested associations of longitudinal loneliness and social-isolation phenotypes with disability, morbidity, mortality, and biological aging through 2018. Results. During follow-up, 18% of older adults met criteria for loneliness and, for 6%, symptoms persisted across two or more follow-up assessments. For social isolation, these fractions were 21% and 8%. HRS participants who experienced loneliness and social isolation were at increased risk for disease, disability, and mortality. Older adults experiencing persistent loneliness were at a 59% increased hazard of mortality compared to those who were never lonely. For social isolation, the increase was 28%. Effect-sizes were somewhat larger for counts of prevalent activity limitations and somewhat smaller for counts of prevalent chronic diseases. Covariate adjustment for socioeconomic and psychological risks attenuated but did not fully explain associations. Older adults who experienced loneliness and social isolation also exhibited physiological indications of advanced biological aging (Cohen's-d for persistent loneliness and social isolation=0.26 and 0.21, respectively). For loneliness, but not social isolation, persistence of symptoms was associated with increased risk. Conclusion. Deficits in social connectedness prevalent in a national sample of older adults in the US were associated with morbidity, disability, and mortality and with more advanced biological aging. Bolstering social connection to interrupt experiences of loneliness may promote healthy aging.
has issue date	2020-07-11(xsd:dateTime)
bibo:doi	10.1101/2020.07.10.20147488
has license	medrxiv
sha1sum (hex)	e3fb0d0bf0325f3e3c2b813339b6104100d865f0
schema:url	https://doi.org/10.1101/2020.07.10.20147488
resource representing a document's title	Associations of Loneliness and Social Isolation with Healthspan and Lifespan in the US Health and Retirement Study
resource representing a document's body	covid:e3fb0d0bf0325f3e3c2b813339b6104100d865f0#body_text
is schema:about of	named entity 'Health' named entity 'Lifespan' named entity 'Loneliness' named entity 'POPULATIONS' covid:arg/e3fb0d0bf0325f3e3c2b813339b6104100d865f0 named entity 'populations' named entity 'social isolation' named entity 'Social Isolation' named entity 'social isolation' named entity 'chronic disease' named entity 'social isolation' named entity 'phenotypic' named entity 'follow-up' named entity 'glucose' named entity 'internal consistency' named entity 'social isolation' named entity 'chronic disease' named entity 'Social and Economic' named entity 'healthy aging' named entity 'depressive symptoms' named entity 'longitudinal data' named entity 'social isolation' named entity 'social isolation' named entity 'medRxiv' named entity 'orange line' named entity 'Cross-sectional studies' named entity 'socially isolated' named entity 'medRxiv' named entity 'chronic disease' named entity 'healthy aging' named entity 'social isolation' named entity 'Longitudinal data' named entity 'Instrumental Activities of Daily Living' named entity 'social isolation' named entity 'medRxiv' named entity 'data collected' named entity 'Linda P. Fried' named entity 'morbidity' named entity 'dummy variable' named entity 'IADL' named entity 'socially isolated' named entity 'RAND corporation' named entity 'social isolation' named entity 'social isolation' named entity 'CC-BY 4.0 International license' named entity 'social isolation' named entity 'social isolation' named entity 'medRxiv' named entity 'social isolation' named entity 'UCLA' named entity 'negative binomial regression' named entity 'social connection' named entity 'biological aging' named entity 'social interactions' named entity 'social and economic' named entity 'healthy aging' named entity 'social isolation' named entity 'social isolation' named entity 'covariate' named entity 'social isolation' named entity 'psychosocial' named entity 'CC-BY 4.0 International license' named entity 'socially isolated' named entity 'social and economic' named entity 'peer review' named entity 'dummy variable' named entity 'Instrumental Activities of Daily Living' named entity 'physical disorder' named entity 'questionnaire' named entity 'UCLA' named entity 'Phenotypic' named entity 'confidence intervals' named entity 'peer review' named entity 'social isolation' named entity 'medRxiv' named entity 'peer review' named entity 'social isolation' named entity 'CC-BY 4.0 International license' named entity 'male or female' named entity 'chronic disease' named entity 'medRxiv'

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