About: Concordance of Chest CT and Nucleic Acid Testing in Diagnosing Coronavirus Disease Outside its District of Origin (Wuhan, China)

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About: Concordance of Chest CT and Nucleic Acid Testing in Diagnosing Coronavirus Disease Outside its District of Origin (Wuhan, China) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Concordance of Chest CT and Nucleic Acid Testing in Diagnosing Coronavirus Disease Outside its District of Origin (Wuhan, China)
Creator	Cao, Jin-Ming Jm, Cao Mu, Qi-Wen Tw, Chen Jq, Yang Lq, Yang Yang, Jian-Qiong Yang, Li-Qin
source	Medline; PMC
abstract	OBJECTIVES: This study aimed to determine the concordance between CT and nucleic acid testing in diagnosing coronavirus disease (COVID-19) outside its district of origin (Wuhan, China). METHODS: Twenty-three consecutive patients with COVID-19, confirmed by nucleic acid testing, were enrolled from two designated hospitals outside the district of disease origin. We collected clinical, laboratory, and CT data and assessed the concordance between CT manifestations and nucleic acid test results by comparing the percentage of patients with and without abnormal CT findings. Furthermore, using Chi-square tests, we analyzed the differences in CT manifestations between patients with and without an exposure history or symptoms. RESULTS: Multiple ground-glass opacities (GGOs), with or without consolidation, were observed on the initial CT scans of 19 patients (82.6%), whereas the remaining 4 (17.4%) showed no CT abnormalities, indicating that the initial chest CT findings were not entirely concordant with the nucleic acid test results in diagnosing COVID-19. Among the latter 4 patients, we observed multiple GGOs with and without consolidation in 2 patients on the follow-up chest CT scans taken on days 7 and 14 after admission, respectively. The remaining 2 patients showed no abnormalities on the follow-up CT scans. Furthermore, abnormal CT findings were found more frequently in patients who had been exposed to COVID-19 in its district of origin than in those who had not been exposed and in symptomatic patients than in asymptomatic patients (all p<0.05). CONCLUSIONS: Patients with positive results on nucleic acid testing may or may not have the abnormal CT manifestations that are frequently found in symptomatic patients with a history of exposure to the district of COVID-19 origin.
has issue date	2020-08-14(xsd:dateTime)
bibo:doi	10.6061/clinics/2020/e1910
bibo:pmid	32844955
has license	cc-by
sha1sum (hex)	e6de8306e6ba9935cbad11facb92ee773b2cb9e5
schema:url	https://doi.org/10.6061/clinics/2020/e1910
resource representing a document's title	Concordance of Chest CT and Nucleic Acid Testing in Diagnosing Coronavirus Disease Outside its District of Origin (Wuhan, China)
has PubMed Central identifier	PMC7426597
has PubMed identifier	32844955
schema:publication	Clinics (Sao Paulo)
resource representing a document's body	covid:e6de8306e6ba9935cbad11facb92ee773b2cb9e5#body_text
is schema:about of	named entity 'positive' named entity 'patients' named entity 'patients' named entity 'abnormal' named entity 'manifestations' named entity 'exposed' named entity 'admission' named entity 'chest' named entity 'USING' named entity 'EXPOSED TO COVID-19' named entity 'ENROLLED' named entity 'DETERMINE' named entity 'CORONAVIRUS DISEASE' named entity 'TESTS' named entity 'NUCLEIC ACID TESTING' covid:arg/e6de8306e6ba9935cbad11facb92ee773b2cb9e5 named entity 'indicating' named entity 'initial' named entity 'testing' named entity 'hospitals' named entity 'patients' named entity 'laboratory' named entity 'frequently' named entity 'determine' named entity 'exposed' named entity 'manifestations' named entity 'Patients' named entity 'initial' named entity 'Both' named entity 'COVID-19' named entity 'COVID' named entity 'acid' named entity 'chest CT' named entity 'nucleic acid testing' named entity 'follow-up' named entity 'China' named entity 'incubation period' named entity 'severe acute respiratory syndrome coronavirus 2' named entity 'COVID' named entity 'infection' named entity 'infection' named entity 'subpleural' named entity 'formative evaluation' named entity 'CT scans' named entity 'COVID' named entity 'collimation' named entity 'viral infection' named entity 'infection' named entity 'nucleic acid testing' named entity 'sputum' named entity 'genomes' named entity 'Hubei Province' named entity 'nucleic acid testing' named entity 'COVID' named entity 'COVID' named entity 'asymptomatic' named entity 'asymptomatic' named entity 'chest CT' named entity 'COVID-19' named entity 'lung diseases' named entity 'infection' named entity 'histopathology' named entity 'virus' named entity 'Prevention and Control' named entity 'lower respiratory tract' named entity 'China' named entity 'CT scans' named entity 'chest CT' named entity 'pulmonary vessels' named entity 'nucleic acid testing' named entity 'clinical symptoms' named entity 'COVID' named entity 'asymptomatic patients' named entity 'Wuhan'

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