About: ECLS in pertussis: does it have a role?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	ECLS in pertussis: does it have a role?
Creator	Williams, G Duffy, B Duffy, × Numa, A Numa, × Sokol, J Sokol, × Tobias, V
source	PMC
abstract	Objectives: To investigate the value of extracorporeal circulatory life support (ECLS) in paediatric patients with severe Bordetella pertussis infection. Design: Single case report and a review of the ECLS database. Setting: Tertiary referral hospital paediatric intensive care unit. Patients and participants: A single case report of an infant with B. pertussis infection is described. Despite receiving ECLS, this infant died from overwhelming cardiac and cerebral insults. Outcome for children receiving ECLS registered on the Extracorporeal Life Support Organization database is reviewed. Measurements and results: The mortality of infants receiving ECLS for B. pertussis infection is high, with only 5 survivors reported among 22 registered cases. The majority of nonsurvivors had evidence of circulatory collapse in addition to severe respiratory failure, and these patients commonly died of hypoxic-ischaemic cerebral insult. These data suggest the existence of a subgroup of patients with respiratory failure only, who may benefit from ECLS, and a larger subgroup who suffer ischaemic cardiac and cerebral insults which are unlikely to be improved by ECLS. Conclusions: The value of ECLS in patients with B. pertussis infection who present with major cardiac dysfunction is questionable. Such patients almost invariably have a poor outcome despite maximal therapy.
has issue date	1998-01-01(xsd:dateTime)
bibo:doi	10.1007/s001340050721
bibo:pmid	9840245
has license	no-cc
sha1sum (hex)	f0f895103e8a6bd9896dfc41a90139a50a4d4e45
schema:url	https://doi.org/10.1007/s001340050721
resource representing a document's title	ECLS in pertussis: does it have a role?
has PubMed Central identifier	PMC7094961
has PubMed identifier	9840245
schema:publication	Intensive Care Med
resource representing a document's body	covid:f0f895103e8a6bd9896dfc41a90139a50a4d4e45#body_text
is schema:about of	named entity 'pertussis' named entity 'INCREASING' named entity 'DISEASE' named entity '5B1' named entity 'HOSPITALISATION' named entity 'HIGHEST' named entity 'PERTUSSIS' named entity '1980' named entity 'develop' named entity 'morbidity' named entity 'radiographically' named entity 'blood count' named entity 'ECLS' named entity 'Ann Arbor, Michigan' named entity 'clinical features' named entity 'Chest X-ray' named entity 'pericardial effusion' named entity 'TCT' named entity 'mucociliary clearance' named entity 'acidosis' named entity 'MAP' named entity 'extracorporeal' named entity 'disseminated intravascular coagulopathy' named entity 'ELSO' named entity 'torr' named entity 'infection' named entity 'alveolar' named entity 'B. pertussis' named entity 'alveolar' named entity 'erythromycin' named entity 'Post-mortem examination' named entity '3.5' named entity 'pertussis' named entity 'ventilator settings' named entity 'Arterial blood gas' named entity 'arterial oxygen saturation' named entity 'haemodynamics' named entity 'ischaemic' named entity 'ischaemic' named entity 'erythromycin' named entity 'extracorporeal' named entity 'B. pertussis' named entity 'oxygen' named entity 'vasodilator' named entity 'blood count' named entity 'hypoxic' named entity 'pertussis' named entity 'echocardiogram' named entity 'aetiological' named entity 'bronchopneumonia' named entity 'respiratory distress' named entity 'ECLS' named entity 'follow-up' named entity 'fibrin' named entity 'ischaemic' named entity 'bicarbonate' named entity 'adverse effects' named entity 'infarction' named entity 'ECLS' named entity 'intubation' named entity 'respiratory failure' named entity 'bicarbonate' named entity 'necrosis' named entity 'diastole' named entity 'echocardiogram' named entity 'oxygen' named entity 'cardiac arrest' named entity 'infection' named entity 'coughing' named entity 'severe respiratory failure' named entity 'torr' named entity 'Pertussis toxin' named entity 'B. pertussis' named entity 'Sydney Children's Hospital'

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