About: Clinical characteristics of IgG4-RD patients infected with COVID-19 in Hubei, China

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About: Clinical characteristics of IgG4-RD patients infected with COVID-19 in Hubei, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical characteristics of IgG4-RD patients infected with COVID-19 in Hubei, China
Creator	Chen, Yu Cai, Shaozhe Chen, # Dong, Lingli Dong, Yuanji Ye, Cong
Source	Elsevier; Medline; PMC
abstract	OBJECTIVE: IgG4-related disease (IgG4-RD) is an immune-mediated multi-organ, chronic and progressive disease. Therefore, we conducted a study to investigate the susceptibility of COVID-19 in IgG4-RD patients in Hubei province, and to characterize the clinical manifestation of COVID-19 in IgG4-RD patients. METHODS: A follow-up system that includes over 200 IgG4-RD patients across the country during the past ten years. A total of ninety-one patients with IgG4-RD who live in Hubei, China were identified and responded to our survey. Medical history, clinical symptoms, laboratory tests, CT imaging, and treatment were obtained through a standardized data collection form, and then independently reviewed by two investigators. RESULTS: 2 of 91 cases were infected with COVID-19. Both of them were classified as moderate type. The symptoms such as fever and cough and radiologic features were similar to other COVID-19 patients. Neither of them episode recurrent of IgG4-RD nor progressed to severe or critical condition of COVID-19 under the condition of continuous oral low-dose of glucocorticoids. Besides, patient 2 took a long time for SARS-CoV-2 nucleic acid to turn negative. CONCLUSION: IgG4-RD patients may belongs to the susceptible population of COVID-19 infection, and thus need more careful personal protection. Early identification and properly treatment are very important to prevent IgG4-RD patients with COVID-19 from progression to severe condition.
has issue date	2020-05-16(xsd:dateTime)
bibo:doi	10.1016/j.semarthrit.2020.04.015
bibo:pmid	32425259
has license	no-cc
sha1sum (hex)	f25777807c31573e39762c67b033c71cfb4716a1
schema:url	https://doi.org/10.1016/j.semarthrit.2020.04.015
resource representing a document's title	Clinical characteristics of IgG4-RD patients infected with COVID-19 in Hubei, China
has PubMed Central identifier	PMC7228889
has PubMed identifier	32425259
schema:publication	Semin Arthritis Rheum
resource representing a document's body	covid:f25777807c31573e39762c67b033c71cfb4716a1#body_text
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