About: Safety of antimicrobial de-escalation for culture-negative severe pneumonia

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Safety of antimicrobial de-escalation for culture-negative severe pneumonia Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Safety of antimicrobial de-escalation for culture-negative severe pneumonia
Creator	Hong, Sang-Bum Koh, Younsuck Lim, Chae-Man Huh, Jin-Won Kwon, Byoung, Soo Choi, Sang
Source	Elsevier; Medline; PMC
abstract	Abstract Purpose This study investigated the outcomes of antimicrobial de-escalation (ADE) based on mortality and the incidence of multi-drug resistant (MDR) pathogen occurrence in patients with culture-negative pneumonia presenting with sepsis and septic shock. Materials and Methods We retrospectively analyzed patients diagnosed with severe pneumonia requiring intensive care unit (ICU) admission and possessing negative microbiological culture results at a tertiary referral hospital in South Korea from March 2008 to July 2018. Results We identified 107 patients with culture-negative pneumonia. The Acute Physiologic and Chronic Health Evaluation (APACHE) II and Sepsis-related Organ Failure Assessment (SOFA) mean scores were 20.3 ± 8.6 and 9.6 ± 3.3, respectively. Among the patients, 40 (37.4%) underwent ADE. The APACHE II, SOFA, and follow-up SOFA scores did not differ significantly between the groups, and no differences were found in ICU mortality and MDR pathogen occurrence (27.5% vs 41.8%, P = .137 and 15.0% vs 16.9% P = .794, respectively). Conclusions We observed similar ICU mortality and MDR pathogen occurrence in patients with culture-negative pneumonia presenting with sepsis/shock regardless of whether they received ADE. Additionally, ADE lowered the antimicrobial burden.
has issue date	2019-12-31(xsd:dateTime)
bibo:doi	10.1016/j.jcrc.2019.06.026
bibo:pmid	31319347
has license	els-covid
sha1sum (hex)	f8613e7a4718a476eb336e8ce23438d98c3f4d6e
schema:url	https://doi.org/10.1016/j.jcrc.2019.06.026
resource representing a document's title	Safety of antimicrobial de-escalation for culture-negative severe pneumonia
has PubMed Central identifier	PMC7126337
has PubMed identifier	31319347
schema:publication	Journal of Critical Care
resource representing a document's body	covid:f8613e7a4718a476eb336e8ce23438d98c3f4d6e#body_text
is schema:about of	named entity 'SAFETY' named entity 'MICROBIOLOGICAL CULTURE' named entity 'ICU' named entity 'DIAGNOSED' named entity 'IDENTIFIED' named entity 'DID' named entity 'ANTIMICROBIAL' named entity 'CULTURE' named entity 'CHRONIC' named entity 'PHYSIOLOGIC' named entity '137' named entity 'GROUPS' named entity 'incidence' named entity 'presenting' named entity 'microbiological culture' named entity 'de-escalation' named entity '8.6' named entity 'DRUG RESISTANT' named entity 'SEVERE PNEUMONIA' named entity 'HEALTH EVALUATION' named entity 'STUDY' named entity 'INTENSIVE CARE UNIT' named entity 'FOLLOW-UP' named entity 'MARCH' named entity 'ADE' named entity 'REGARDLESS' named entity 'LOWERED' named entity 'FAILURE ASSESSMENT' named entity 'NEGATIVE' named entity 'OBSERVED' named entity 'PATIENTS' named entity 'PATHOGEN' named entity 'RELATED' named entity 'ADMISSION' named entity 'SCORES' named entity 'INVESTIGATED' named entity 'SOUTH KOREA' named entity '107' named entity 'JULY' named entity '3.3' named entity 'TERTIARY REFERRAL HOSPITAL' named entity 'SEPSIS' named entity 'MULTI' named entity '2018' named entity 'SEVERE PNEUMONIA' named entity 'ESCALATION' named entity 'METHODS' named entity 'MDR' named entity 'SEPTIC SHOCK' named entity 'PURPOSE' named entity 'PRESENTING' named entity 'CONCLUSIONS' named entity 'MATERIALS' named entity 'ACUTE' named entity 'ESCALATION' named entity 'SOFA' named entity 'BURDEN' named entity 'OCCURRENCE' named entity 'PNEUMONIA' named entity 'FOUND' named entity 'RECEIVED' named entity 'NEGATIVE' named entity 'ANTIMICROBIAL' named entity 'CULTURE' named entity 'INCIDENCE' named entity 'ANALYZED' named entity 'MEAN' named entity 'ORGAN FAILURE' named entity 'OUTCOMES' named entity 'SIMILAR' named entity 'BASED' named entity '20.3' named entity 'MORTALITY' named entity 'APACHE II' named entity 'RESULTS'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software