About: Outcomes of patients with end-stage kidney disease hospitalized with COVID-19

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Outcomes of patients with end-stage kidney disease hospitalized with COVID-19
Creator	Jhaveri, Kenar Ng, Jia Hirsch, Jamie Fishbane, Steven Wanchoo, Rimda Hong, Susana Sachdeva, Mala Sakhiya, Vipulbhai
Source	Elsevier; Medline; PMC
abstract	Given the high risk of infection-related mortality, patients with end-stage kidney disease (ESKD) may be at increased risk with COVID-19. To assess this, we compared outcomes of patients with and without ESKD, hospitalized with COVID-19. This was a retrospective study of patients admitted with COVID-19 from 13 New York. hospitals from March 1, 2020, to April 27, 2020, and followed through May 27, 2020. We measured primary outcome (in-hospital death), and secondary outcomes (mechanical ventilation and length of stay), Of 10,482 patients with COVID-19, 419 had ESKD. Patients with ESKD were older, had a greater percentage self-identified as Black, and more comorbid conditions. Patients with ESKD had a higher rate of in-hospital death than those without (31.7% vs 25.4%, odds ratio 1.38, 95% confidence interval 1.12 - 1.70). This increase rate remained after adjusting for demographic and comorbid conditions (adjusted odds ratio 1.37, 1.09 - 1.73). The odds of length of stay of seven or more days was higher in the group with compared to the group without ESKD in both the crude and adjusted analysis (1.62, 1.27 - 2.06; vs 1.57, 1.22 - 2.02, respectively). There was no difference in the odds of mechanical ventilation between the groups. Independent risk factors for in-hospital death for patients with ESKD were increased age, being on a ventilator, lymphopenia, blood urea nitrogen and serum ferritin. Black race was associated with a lower risk of death. Thus, among patients hospitalized with COVID-19, those with ESKD had a higher rate of in-hospital death compared to those without ESKD.
has issue date	2020-08-15(xsd:dateTime)
bibo:doi	10.1016/j.kint.2020.07.030
bibo:pmid	32810523
has license	no-cc
sha1sum (hex)	f9c7e1f0cc2ca6b49a81f977d5d92fb24e4e4c95
schema:url	https://doi.org/10.1016/j.kint.2020.07.030
resource representing a document's title	Outcomes of patients with end-stage kidney disease hospitalized with COVID-19
has PubMed Central identifier	PMC7428720
has PubMed identifier	32810523
schema:publication	Kidney Int
resource representing a document's body	covid:f9c7e1f0cc2ca6b49a81f977d5d92fb24e4e4c95#body_text
is schema:about of	named entity 'end-stage kidney disease' named entity 'patients' named entity 'Outcomes' named entity 'ESKD' named entity 'ACE inhibitors' named entity 'renal transplant' named entity 'patients' named entity 'COVID-19' named entity 'end-stage kidney disease' named entity 'COVID-19' named entity 'end-stage kidney disease' named entity 'ESKD' named entity 'ESKD' named entity 'ESKD' named entity 'ESKD' named entity 'BMI' named entity 'risk factors' named entity 'general population' named entity 'access to medical care' named entity 'United States' named entity 'dialysis' named entity 'ICU' named entity 'ESKD' named entity 'dialysis' named entity 'mechanical ventilation' named entity 'clinical characteristics' named entity 'risk of death' named entity 'United States' named entity 'RAAS' named entity 'risk factors' named entity 'mechanical ventilation' named entity 'ESKD' named entity 'rate of mortality' named entity 'risk of death' named entity 'United Kingdom' named entity 'medical history' named entity 'COVID-19' named entity 'ESKD' named entity 'host immunity' named entity 'coagulation' named entity 'ESKD' named entity 'ESKD' named entity 'angiotensin-converting enzyme (ACE) inhibitor' named entity 'fight infection' named entity 'serum ferritin' named entity 'EHR' named entity 'New York' named entity 'mechanical ventilation' named entity 'preprint' named entity 'Nephrology' named entity 'ACE inhibitors' named entity 'risk factors' named entity 'statistically significant' named entity 'C-reactive protein' named entity 'ESKD' named entity 'Dialysis' named entity 'ARBs' named entity 'ESKD' named entity 'asthma' named entity 'renal transplant' named entity 'dialysis' named entity 'risk factors' named entity 'remdesivir' named entity 'ESKD' named entity 'ESKD' named entity 'vasopressor' named entity 'preprint' named entity 'renal transplant' named entity 'laboratory tests' named entity 'statistical analyses' named entity 'Inflammatory markers' named entity 'hemodialysis' named entity 'ICU' named entity 'txp'

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