About: An examination of the ability of titanium dioxide nanoparticles and its conjugates with oligonucleotides to penetrate into eucariotis cells

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About: An examination of the ability of titanium dioxide nanoparticles and its conjugates with oligonucleotides to penetrate into eucariotis cells Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	An examination of the ability of titanium dioxide nanoparticles and its conjugates with oligonucleotides to penetrate into eucariotis cells
Creator	Balakhnin, S Belanov, E Evdokimov, A Ismagilov, Z Levina, A Repkova, M Shikina, N Zarytova, V Zinov'ev, V
topic	covid:ffa4440314406bc74fafc1b39b06871b5949d7bf#this
Source	PMC
abstract	In this study we examine the possibility that TiO(2) nanoparticles and their conjugates can penetrate into cultivated cells without any special transfection procedures. Oligonucleotides and their derivates were conjugated with the TiO(2) nanoparticles, which were obtained as colloidal solutions at a concentration of TiO(2) 0.3M by TiCl(4) hydrolysis. The electronic microscopy of various cell cultures (KCT, Vero, and MDCK) treated with nanoparticle solutions (20 µg/µl) showed that nanoparticles could enter the cells and accumulate in the vacuoles and phagosomes and form inclusions in cytoplasm. Thus, we demonstrated the penetration of TiO(2) nanoparticles and their oligonucleotide conjugates into intracellular space without any auxiliary operations. Most other researches used electroporation techniques for similar purposes [1, 2, 5].
has issue date	2009-10-20(xsd:dateTime)
bibo:doi	10.1134/s1995078009090158
bibo:pmid	32218897
has license	no-cc
sha1sum (hex)	ffa4440314406bc74fafc1b39b06871b5949d7bf
schema:url	https://doi.org/10.1134/s1995078009090158
resource representing a document's title	An examination of the ability of titanium dioxide nanoparticles and its conjugates with oligonucleotides to penetrate into eucariotis cells
has PubMed Central identifier	PMC7090768
has PubMed identifier	32218897
schema:publication	Nanotechnol Russ
resource representing a document's body	covid:ffa4440314406bc74fafc1b39b06871b5949d7bf#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/ffa4440314406bc74fafc1b39b06871b5949d7bf
is schema:about of	named entity 'nanoparticles' named entity 'electroporation' named entity 'cell cultures' named entity 'procedures' named entity 'CONJUGATES' named entity 'CONCENTRATION OF' named entity 'OPERATIONS' named entity 'CONJUGATED' named entity 'NANOPARTICLES' named entity 'Vero' named entity 'inclusions' named entity 'Thus' named entity 'conjugates' named entity 'special' named entity 'enter' named entity 'Oligonucleotides' named entity 'oligonucleotide' named entity 'nanoparticles' named entity 'nanoparticles' named entity 'nanoparticles' named entity 'vacuoles' named entity 'colloidal solutions' named entity 'cells' named entity 'Flu' named entity 'TiO' named entity 'microphotography' named entity 'laser microscopy' named entity 'oligonucleotides' named entity 'nano particles' named entity 'bioactive' named entity 'brookite' named entity 'nanoparticles' named entity 'viral diseases' named entity 'DAPI' named entity 'laser scanning microscope' named entity 'antibiotic' named entity 'AFM' named entity 'mitochondria' named entity 'Nanoparticles' named entity 'complex formation' named entity 'sec' named entity 'nanoparticles' named entity 'DAPI' named entity 'TiO' named entity '1, 2' named entity 'genetic material' named entity 'streptomycin' named entity 'anticancer drug' named entity 'citrate' named entity 'PBS' named entity 'oligo' named entity 'nucleases' named entity 'electronic microscope' named entity 'colloidal solution' named entity 'nanoparticles' named entity 'antisense oligonucleotides' named entity 'oligo' named entity 'nanoparticles' named entity 'TiO' named entity 'apoptotic' named entity 'nanoparticles' named entity 'instat' named entity 'Araldite' named entity 'nanoparticles' named entity 'bacteria' named entity 'plumbum' named entity 'erbB2' named entity 'Flu' named entity 'Leica' named entity 'PBS' named entity 'gene'

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