About: Comparison of SARS-CoV-2 detection in nasopharyngeal swab and saliva

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Comparison of SARS-CoV-2 detection in nasopharyngeal swab and saliva
Creator	Sato, Kaori Fujisawa, Shinichi Hayasaka, Kasumi Iwasaki, Sumio Kamada, Keisuke Konno, Satoshi Nakakubo, Sho Nishida, Mutsumi Teshima, Takanori Yamashita, Yu Fukumoto, Tatsuya Oguri, Satoshi Senjo, Hajime Taki, Keisuke
source	MedRxiv
abstract	We prospectively compared the efficacy of PCR detection of SARS-CoV-2 between paired nasopharyngeal and saliva samples in nine COVID-19 patients. SARS-CoV-2 was detected in saliva in 8 of 9 (89%) patients and in all 11 samples taken within 2 weeks after disease onset. Viral load was equivalent at earlier time points but declined in saliva than nasopharyngeal samples. PCR negativity was also concordant in all 27 saliva samples from 24 patients between nasopharyngeal and saliva samples. These results suggest that saliva is a reliable noninvasive alternative to nasopharyngeal swabs and facilitate widespread PCR testing in the face of shortages of swabs and protective equipment without posing a risk to healthcare workers.
has issue date	2020-05-19(xsd:dateTime)
bibo:doi	10.1101/2020.05.13.20100206
has license	medrxiv
sha1sum (hex)	ffff2fb21d4880b63a7cf3849cecc45bc596f4f0
schema:url	https://doi.org/10.1101/2020.05.13.20100206
resource representing a document's title	Comparison of SARS-CoV-2 detection in nasopharyngeal swab and saliva
resource representing a document's body	covid:ffff2fb21d4880b63a7cf3849cecc45bc596f4f0#body_text
is schema:about of	named entity 'healthcare' named entity 'samples' named entity 'weeks' named entity 'saliva' named entity 'saliva sample' named entity 'Running' covid:arg/ffff2fb21d4880b63a7cf3849cecc45bc596f4f0 named entity 'patients' named entity 'nasopharyngeal' named entity 'protective equipment' named entity 'time' named entity 'Viral load' named entity 'saliva' named entity 'PCR' named entity 'COVID' named entity 'SARS-CoV-2' named entity 'PCR' named entity 'saliva samples' named entity 'saliva' named entity 'SARS-CoV-2' named entity 'saliva sample' named entity 'saliva' named entity 'nasopharyngeal' named entity 'infection' named entity 'sense of taste' named entity 'virus' named entity 'saliva samples' named entity 'symptom' named entity 'coronavirus disease 2019' named entity 'PCR testing' named entity 'nasopharynx' named entity 'nasopharyngeal swabs' named entity 'PCR' named entity 'medRxiv' named entity 'saliva' named entity 'Nasopharyngeal' named entity 'COVID' named entity 'statistical significance' named entity 'nasopharyngeal' named entity 'saliva' named entity 'Median age' named entity 'Japan' named entity 'protective equipment' named entity 'nasopharyngeal swabs' named entity 'saliva samples' named entity 'COVID' named entity 'COVID' named entity 'SARS-CoV-2' named entity 'saliva' named entity 'virus' named entity 'virus' named entity 'symptom' named entity 'medRxiv' named entity 'Tokyo' named entity 'COPAN' named entity 'epithelial cells' named entity 'saliva samples' named entity 'nasopharyngeal' named entity 'nasopharyngeal' named entity 'SARS-CoV-2' named entity 'viral load' named entity 'saliva' named entity 'saliva samples' named entity 'nasopharyngeal' named entity 'COVID-19' named entity 'nasopharyngeal swabs' named entity 'oral cavity' named entity 'PCR testing' named entity 'COVID' named entity 'saliva samples' named entity 'saliva samples' named entity 'PCR'

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