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Polyketide synthases (PKSs) are a family of multi-domain enzymes or enzyme complexes that produce polyketides, a large class of secondary metabolites, in bacteria, fungi, plants, and a few animal lineages. The biosyntheses of polyketides share striking similarities with fatty acid biosynthesis. The PKS genes for a certain polyketide are usually organized in one operon or in gene clusters. Type I and type II PKSs form either large modular protein complexes or dissociable molecular assemblies; type III PKSs exist as smaller homodimeric proteins.

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type
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  • Polyketide synthase
  • Policétido sintasa
  • Polycétide synthase
  • Policétido sintase
  • Поликетидсинтаза
  • ポリケチド合成酵素
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  • Una policétido sintasa (PKS) es un complejo multienzimático que biosintetiza precursores de productos naturales denominados policétidos.​
  • Поликетидсинтазы (ПКС, англ. Polyketide synthase, КФ 6.4) — ферменты или мультиферментные комплексы, синтезирующие поликетиды (вторичные метаболиты, такие как антибиотики, токсины или статины). Поликетидсинтазы обнаружены у бактерий, грибов, животных и растений и имеют большое сходство с синтазами жирных кислот в организации и механизме биосинтеза. Как правило, гены синтазы определённого поликетида входят в один оперон (у бактерий) или в один кластер (у эукариот).
  • Une polycétide synthase est une enzyme multifonctionnelle ou un complexe enzymatique produisant des polycétides, une grande famille de métabolites secondaires chez les bactéries, les mycètes, les plantes et certaines lignées d'animaux. La biosynthèse des polycétides présente des ressemblances frappantes avec la biosynthèse des acides gras réalisée par l'acide gras synthase. Les gènes codant les polycétide synthases sont organisés en opéron chez les bactéries et en clusters de gènes chez les eucaryotes. On distingue trois types de polycétides synthases :
  • Policétido sintases (abreviadas na literatura como PKSs, de polyketide synthases) são uma família de enzimas multi-domínio ou complexos enzimáticos que produzem , uma ampla classe de metabólitos secundários, em bactérias, fungos, plantas, e uma poucas linhagens de animais. As biossínteses de policétidos compartilham semelhanças impressionantes com a biossíntese de ácidos graxos. Os genes PKS para um certo policétido são normalmente organizados em um operon em bactérias e em em eucariotas.
  • Polyketide synthases (PKSs) are a family of multi-domain enzymes or enzyme complexes that produce polyketides, a large class of secondary metabolites, in bacteria, fungi, plants, and a few animal lineages. The biosyntheses of polyketides share striking similarities with fatty acid biosynthesis. The PKS genes for a certain polyketide are usually organized in one operon or in gene clusters. Type I and type II PKSs form either large modular protein complexes or dissociable molecular assemblies; type III PKSs exist as smaller homodimeric proteins.
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