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Vicriviroc, previously named SCH 417690 and SCH-D, is a pyrimidine CCR5 entry inhibitor of HIV-1. It was developed by the pharmaceutical company Schering-Plough. Merck decided to not pursue regulatory approval for use in treatment-experienced patients because the drug did not meet primary efficacy endpoints in late stage trials. Clinical trials continue in patients previously untreated for HIV.

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  • Vicriviroc
  • Vicriviroc
  • فيكريفيروك
  • ビクリビロク
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  • ビクリビロク（Vicriviroc）は、ピリミジン系のHIV-1のCCR5エントリー阻害剤である。以前はSCH 417690やSCH-Dと呼ばれていた。製薬会社シェリング・プラウ社が開発した。メルク社は、後期臨床試験において主要な有効性評価項目を満たさなかったため、治療経験のある患者への使用について規制当局の承認を求めないことを決定した。治療未経験の患者を対象とした臨床試験は継続している。
  • Vicriviroc, previously named SCH 417690 and SCH-D, is a pyrimidine CCR5 entry inhibitor of HIV-1. It was developed by the pharmaceutical company Schering-Plough. Merck decided to not pursue regulatory approval for use in treatment-experienced patients because the drug did not meet primary efficacy endpoints in late stage trials. Clinical trials continue in patients previously untreated for HIV.
  • فيكريفيروك هو مثبط دخول بيريميدينلبروتين CCR5 لفيروس العوز المناعي . تم تطويره من قبل شركة الأدوية شيرينغ بلاو .
  • Le vicriviroc (DCI) est une molécule qui a été envisagée comme médicament antirétroviral. C’est un inhibiteur du récepteur CCR5 présent sur les globules blancs. Ce projet de médicament fait partie des VIH-m-tropiques, c'est-à-dire qu'il vise à empêcher la reproduction du virus de l'immunodéficience humaine (VIH) en interdisant son association avec les macrophages. Ce médicament n'est pas commercialisé, mais poursuit sa phase de test en 2010.
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