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About:
Thrombotic complications and anticoagulation in COVID-19 pneumonia: a New York City hospital experience
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
wasabi.inria.fr
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document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Thrombotic complications and anticoagulation in COVID-19 pneumonia: a New York City hospital experience
Creator
Adrish, Muhammad
Alla, Yamini
Attwood, Kristopher
Chinta, Siddharth
Hanif, Ahmad
Hanif, Sana
Jain, Kevin
Ji, Wenyan
Khan, Sumera
Mantri, Nikhitha
Saleh, Muhamed
Shrestha, Nikee
Source
Medline; PMC
abstract
Infection with SARS-CoV-2 (COVID-19) can cause prothrombotic complications. We aim to study the frequency of thrombotic complications and impact of anticoagulation on outcomes in hospitalized patients. We conducted a retrospective chart review of 921 consecutive patients admitted to our hospital with COVID-19. Patients were divided into four groups depending on whether they were on anticoagulation prior to admission, started anticoagulation during the admission, received prophylactic anticoagulation, or did not receive any anticoagulation. At the time of analysis, 325 patients (35.3%) had died, while 544 patients (59%) had been discharged resulting in inpatient mortality of 37.3%. Male sex, age > 65 years, and high D-dimer at admission were associated with higher mortality. Sixteen patients (1.7%) had venous thromboembolism confirmed with imaging, 11 patients had a stroke, and 2 patients developed limb ischemia. Treatment with therapeutic anticoagulation was associated with improved inpatient mortality compared with prophylactic anticoagulation alone (63% vs 86.2%, p < 0.0001) in patients requiring mechanical ventilation. Other outcomes such as rates of liberation from mechanical ventilation and duration of mechanical ventilation were not significantly impacted by the type of anticoagulation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00277-020-04216-x) contains supplementary material, which is available to authorized users.
has issue date
2020-08-17
(
xsd:dateTime
)
bibo:doi
10.1007/s00277-020-04216-x
bibo:pmid
32808105
has license
no-cc
sha1sum (hex)
011f0f03c6f952339a571428f824810fa8809564
schema:url
https://doi.org/10.1007/s00277-020-04216-x
resource representing a document's title
Thrombotic complications and anticoagulation in COVID-19 pneumonia: a New York City hospital experience
has PubMed Central identifier
PMC7430929
has PubMed identifier
32808105
schema:publication
Ann Hematol
resource representing a document's body
covid:011f0f03c6f952339a571428f824810fa8809564#body_text
is
schema:about
of
named entity 'aim'
named entity 'thrombotic complications'
named entity 'Sixteen'
named entity 'D-dimer'
named entity 'frequency'
named entity 'anticoagulation'
named entity 'DIVIDED'
named entity 'DID'
named entity 'divided'
named entity 'inpatient'
named entity 'patients'
named entity 'COVID-19'
named entity 'patients'
named entity 'Male'
named entity 'mechanical ventilation'
named entity 'high'
named entity 'patients'
named entity 'impacted'
named entity 'Patients'
named entity 'started'
named entity 'complications'
named entity 'compared'
named entity 'D-dimer'
named entity 'mechanical ventilation'
named entity 'anticoagulation'
named entity 'anticoagulation'
named entity 'COVID'
named entity 'Thrombotic complications'
named entity 'pneumonia'
named entity 'COVID'
named entity 'anticoagulation'
named entity 'D-dimer'
named entity 'D-dimer'
named entity 'intubated'
named entity 'COVID-19'
named entity 'anticoagulation'
named entity 'mechanical ventilation'
named entity 'prophylactic'
named entity 'anticoagulation'
named entity 'SARS-CoV-2'
named entity 'D-dimer'
named entity 'transfusion'
named entity 'severe acute respiratory syndrome coronavirus 2'
named entity 'respiratory infection'
named entity 'anticoagulation'
named entity 'thrombotic complications'
named entity 'anticoagulation'
named entity 'clinically significant'
named entity 'SARS CoV'
named entity 'mechanical ventilation'
named entity 'anticoagulation'
named entity 'D-dimer'
named entity 'anticoagulation'
named entity 'D-dimer'
named entity 'autopsy'
named entity 'anticoagulation'
named entity 'COVID'
named entity 'low molecular weight heparin'
named entity 'univariate analysis'
named entity 'COVID'
named entity 'anticoagulation'
named entity 'D-dimer'
named entity 'New York City'
named entity 'Fisher's exact test'
named entity 'anticoagulation'
named entity 'New York City'
named entity 'pneumonia'
named entity 'mechanical ventilation'
named entity 'respiratory support'
named entity 'anticoagulation'
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