About: COVID-19 and Cardiac Arrhythmias

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	COVID-19 and Cardiac Arrhythmias
Creator	Lin, David Abella, Benjamin Anesi, George Arkles, Jeffrey Ba, Michael Bhatla, Anjali Bullinga, John Callans, David Chahal, Anwar Denduluri, Srinivas Deo, Rajat Dixit, Sanjay Domenico, Christopher Epstein, Andrew Frankel, David Garcia, Fermin Kumareswaram, Ramanan Marchlinski, Francis Moss, Juwann Nazarian, Saman Oh, Eric Riley, Michael Santangeli, Pasquale Schaller, Robert Supple, Gregory Tierney, Ann Adusumalli, Matthew Hyman, Mayer, Srinath
source	Elsevier; Medline; PMC
abstract	BACKGROUND: Early studies suggest that coronavirus disease 2019 (COVID-19) is associated with a high incidence of cardiac arrhythmias. SARS-CoV-2 infection may cause injury to cardiac myocytes and increase arrhythmia risk. OBJECTIVE: To evaluate the risk of cardiac arrest and arrhythmias including incident atrial fibrillation (AF), bradyarrhythmias, and nonsustained ventricular tachycardia (NSVT) in a large urban population hospitalized for COVID-19. We also evaluated correlations between the presence of these arrhythmias and mortality. METHODS: We reviewed the characteristics of all COVID-19 patients admitted to our center over a 9-week period. Throughout hospitalization, we evaluated the incidence of cardiac arrests, arrhythmias and in-patient mortality. We also used logistic regression to evaluate age, sex, race, body mass index, prevalent cardiovascular disease, diabetes, hypertension, kidney disease and ICU status as potential risk factors for each arrhythmia. RESULTS: Among 700 patients (mean age 50±18 years, 45% men, 71% African American, and 11% received ICU care), there were 9 cardiac arrests, 25 incident AF events, 9 clinically significant bradyarrhythmias, and 10 NSVTs. All cardiac arrests occurred among patients admitted to the ICU. In addition, admission to the ICU was associated with incident AF (OR 4.68 [95% CI 1.66 – 13.18]) and NSVT (OR 8.92 [95% CI 1.73 – 46.06]) after multivariable adjustment. Also, age and incident AF (OR 1.05 [95% CI 1.02 – 1.09]); and prevalent heart failure and bradyarrhythmias (OR 9.75 [95% CI 1.95 – 48.65]) were independently associated. Only cardiac arrests were associated with acute, in-hospital mortality. CONCLUSION: Cardiac arrests and arrhythmias are likely the consequence of systemic illness and not solely the direct effects of COVID-19 infection.
has issue date	2020-06-22(xsd:dateTime)
bibo:doi	10.1016/j.hrthm.2020.06.016
bibo:pmid	32585191
has license	no-cc
sha1sum (hex)	0252be72cc29aae7154f0c67d9b411583a31bea7
schema:url	https://doi.org/10.1016/j.hrthm.2020.06.016
resource representing a document's title	COVID-19 and Cardiac Arrhythmias
has PubMed Central identifier	PMC7307518
has PubMed identifier	32585191
schema:publication	Heart Rhythm
resource representing a document's body	covid:0252be72cc29aae7154f0c67d9b411583a31bea7#body_text
is schema:about of	named entity 'CONSEQUENCE OF' named entity 'ARRESTS' named entity 'systemic illness' named entity 'direct effects' named entity 'arrhythmias' named entity 'long-term' named entity 'Comorbid conditions' named entity 'D-dimer' named entity 'diabetes' named entity 'biomarker' named entity 'arrhythmias' named entity 'single center' named entity 'ventricular fibrillation' named entity 'ventricular tachycardia' named entity 'amiodarone' named entity 'medical chart' named entity 'BNP' named entity 'atrial arrhythmias' named entity 'cardiac arrest' named entity 'systemic illness' named entity 'ICU' named entity 'BNP' named entity 'logistic regression' named entity 'laboratory tests' named entity 'troponin' named entity 'bradyarrhythmias' named entity 'COVID' named entity 'BMI' named entity 'antiviral medications' named entity 'asystole' named entity 'African American' named entity 'NSVT' named entity 'bradyarrhythmias' named entity 'CHD' named entity 'ICU' named entity 'OSA' named entity 'ICU' named entity 'ICU' named entity 'high sensitivity C-reactive protein' named entity 'troponin' named entity 'bradyarrhythmias' named entity 'ICU' named entity 'ICU' named entity 'COVID-19' named entity 'heart failure' named entity 'inpatient admissions' named entity 'ICU' named entity 'heart failure' named entity 'obstructive sleep apnea' named entity 'ICU' named entity 'ICU' named entity 'NSVT' named entity 'bradyarrhythmias'

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