About: Antibiotics nonadherence and knowledge in a community with the world’s leading prevalence of antibiotics resistance: Implications for public health intervention

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About: Antibiotics nonadherence and knowledge in a community with the world’s leading prevalence of antibiotics resistance: Implications for public health intervention Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Antibiotics nonadherence and knowledge in a community with the world’s leading prevalence of antibiotics resistance: Implications for public health intervention
Creator	Chow, Wing-Cheong Fok, Chun-Man Lam, Tai-Hing Sin, Chun-Fung Wong, Kwok-Kei Wong, Sze-Man Lok, Zara Mbbs, Mandy Mbbs, Michael Mbbs, Roanna Mbbs, Yap-Hang Schooling, C Yeung, Terence
source	Elsevier; Medline; PMC
abstract	Background Community determinants of antibiotics nonadherence, an important contributor of antibiotics resistance, remained unclear. Objectives Our objective was to investigate whether deficient antibiotics knowledge could contribute to nonadherence in a community with high prevalence of antibiotics resistance. Methods We recruited 465 people by random sampling from 5 urban areas in Hong Kong. A structured questionnaire was used to assess antibiotics knowledge and adherence. Adherence was defined as completing the most recent course of antibiotics entirely according to physicians’ instructions. An antibiotics knowledge score ranging from 0 to 3 (highest) was composed based on the number of correctly answered questions. Results Of the 465 participants interviewed, 96.3% had heard of the term “antibiotics,” and 80.6% recalled having previously received antibiotics prescription. Among the eligible 369 subjects, 32.9% showed nonadherence. Percentages of participants with antibiotics knowledge scores of 0, 1, 2, and 3 were 11%, 27%, 33%, and 29%, respectively. There was a higher prevalence of nonadherence among people with lower antibiotics knowledge score (P < .001). Furthermore, people with nonadherence had a significantly lower mean antibiotics knowledge score (1.3 ± 1.0 versus 2.0 ± 0.9, P < .001), with no interaction with education (P < .05). Adjusted for potential confounders, antibiotics knowledge scores of 2, 1, and 0 independently predicted increased risk of nonadherence by 1-fold (odds ratio [OR], 2.00; 95% confidence interval [CI]: 1.01-3.94; P = .047), 4-fold (OR, 4.77; 95% CI: 2.30-9.92; P < .001), and 17-fold (OR, 18.41; 95% CI: 6.92-48.97; P < .001) respectively, compared with the maximum score of 3. Conclusion Lack of antibiotics knowledge is a critical determinant of nonadherence independent of education in the community.
has issue date	2012-03-31(xsd:dateTime)
bibo:doi	10.1016/j.ajic.2011.03.017
bibo:pmid	21741119
has license	els-covid
sha1sum (hex)	02b60c38bd61ad41928b07c72f049390d6848a3f
schema:url	https://doi.org/10.1016/j.ajic.2011.03.017
resource representing a document's title	Antibiotics nonadherence and knowledge in a community with the world’s leading prevalence of antibiotics resistance: Implications for public health intervention
has PubMed Central identifier	PMC7115258
has PubMed identifier	21741119
schema:publication	American Journal of Infection Control
resource representing a document's body	covid:02b60c38bd61ad41928b07c72f049390d6848a3f#body_text
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