About: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Dromedary Camels in Africa and Middle East

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About: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Dromedary Camels in Africa and Middle East Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Dromedary Camels in Africa and Middle East
Creator	Peiris, Malik Kayali, Ghazi Abiadh, Awatef Amr, Zuhair Attar, Roba Bagato, Ola El-Shesheny, Rabeh Elsokary, Basma Gomaa, Mokhtar Hassan, Nagla Jrijer, Jamel Kandeil, Ahmed Kutkat, Omnia Mahmoud, Sara Moatassim, Yassmin Mostafa, Ahmed Nageh, Ahmed Saad, Ahmed Sobhy, Heba Tugume, Titus Wabwire-Mangen, Fred Makonnen, Yilma Chu, Daniel Shehata, Mahmoud Webby, Richard Ali, Mohamed Byarugaba, Denis Perera, Ranawaka Abo, Noura Hassan, Sabah Kayed, Ahmed Linjawi, Sabah Masry, Ihab Mckenzie, Pamela Mohamed, Nadira Sabir, Jamal Said, Mounir
source	Medline; PMC
abstract	Dromedary camels are the natural reservoirs of the Middle East respiratory syndrome coronavirus (MERS-CoV). Camels are mostly bred in East African countries then exported into Africa and Middle East for consumption. To understand the distribution of MERS-CoV among camels in North Africa and the Middle East, we conducted surveillance in Egypt, Senegal, Tunisia, Uganda, Jordan, Saudi Arabia, and Iraq. We also performed longitudinal studies of three camel herds in Egypt and Jordan to elucidate MERS-CoV infection and transmission. Between 2016 and 2018, a total of 4027 nasal swabs and 3267 serum samples were collected from all countries. Real- time PCR revealed that MERS-CoV RNA was detected in nasal swab samples from Egypt, Senegal, Tunisia, and Saudi Arabia. Microneutralization assay showed that antibodies were detected in all countries. Positive PCR samples were partially sequenced, and a phylogenetic tree was built. The tree suggested that all sequences are of clade C and sequences from camels in Egypt formed a separate group from previously published sequences. Longitudinal studies showed high seroprevalence in adult camels. These results indicate the widespread distribution of the virus in camels. A systematic active surveillance and longitudinal studies for MERS-CoV are needed to understand the epidemiology of the disease and dynamics of viral infection.
has issue date	2019-08-05(xsd:dateTime)
bibo:doi	10.3390/v11080717
bibo:pmid	31387326
has license	cc-by
sha1sum (hex)	03f315449023c980e42af7eb150d0cd9cab57f5a
schema:url	https://doi.org/10.3390/v11080717
resource representing a document's title	Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Dromedary Camels in Africa and Middle East
has PubMed Central identifier	PMC6723520
has PubMed identifier	31387326
schema:publication	Viruses
resource representing a document's body	covid:03f315449023c980e42af7eb150d0cd9cab57f5a#body_text
is schema:about of	named entity 'sequences' named entity 'natural reservoirs' named entity 'North Africa' named entity 'Dromedary' named entity 'Middle East Respiratory Syndrome Coronavirus' named entity 'MERS-CoV' named entity 'TUNISIA' named entity 'EPIDEMIOLOGY' named entity '3267' named entity 'SEPARATE' named entity 'AFRICAN' named entity 'PHYLOGENETIC TREE' named entity 'NEEDED' named entity 'NORTH AFRICA' named entity 'IRAQ' named entity 'SAUDI ARABIA' named entity 'POSITIVE' named entity 'MERS-COV RNA' named entity 'COUNTRIES' named entity 'DISEASE' named entity 'SERUM' named entity 'CLADE' named entity 'TRANSMISSION' named entity 'CAMEL' named entity 'NASAL SWABS' named entity '2018' named entity 'VIRUS' named entity 'TOTAL' named entity 'WIDESPREAD' named entity 'PREVIOUSLY' named entity 'CONSUMPTION' named entity 'GROUP' named entity 'DETECTED' named entity 'FORMED' named entity 'PCR' named entity 'MIDDLE EAST' named entity 'TREE' named entity 'BRED' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'RESERVOIRS' named entity 'DISTRIBUTION' named entity 'HIGH' named entity 'CAMELS' named entity 'AFRICA' named entity 'RESULTS'

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