About: Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe

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About: Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe
Creator	Halbur, P Lum, M Meng, X.-J Paul, P
Source	PMC
abstract	The putative membrane (M) protein (ORF 6) and nucleocapsid (N) protein (ORF 7) genes of five U.S. isolates of porcine reproductive and respiratory syndrome virus (PRRSV) with differing virulence were cloned and sequenced. To determine the genetic variation and the phylogenetic relationship of PRRSV, the deduced amino acid sequences of the putative M and N proteins from these isolates were aligned, to the extent known, with other PRRSV isolates, and also other members of the proposed arterivirus group including lactate dehydrogenase-elevating virus (LDV) and equine arteritis virus (EAV). There was 96–100% amino acid sequence identity in the putative M and N genes among U.S. and Canadian PRRSV isolates with differing virulence. However, their amino acid sequences varied extensively from those of European PRRSV isolates, and displayed only 57–59% and 78–81% identity, respectively. The phylogenetic trees constructed on the basis of the putative M and N genes of the proposed arterivirus group were similar and indicated that both U.S. and European PRRSV isolates were related to LDV and were distantly related to EAV. The U.S. and European PRRSV isolates fell into two distinct groups, suggesting that U.S. and European PRRSV isolates represent two distinct genotypes.
has issue date	1995-01-01(xsd:dateTime)
bibo:doi	10.1007/bf01309962
bibo:pmid	7794115
has license	no-cc
sha1sum (hex)	045ca16ba40806eadbfe0b8f420cb81bea7c10b5
schema:url	https://doi.org/10.1007/bf01309962
resource representing a document's title	Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe
has PubMed Central identifier	PMC7086766
has PubMed identifier	7794115
schema:publication	Arch Virol
resource representing a document's body	covid:045ca16ba40806eadbfe0b8f420cb81bea7c10b5#body_text
is schema:about of	named entity 'GENOTYPES' named entity 'PHYLOGENETIC RELATIONSHIP' named entity 'DISPLAYED' named entity 'GENETIC VARIATION' named entity 'CONSTRUCTED' named entity 'AMINO ACID SEQUENCE' named entity 'IDENTITY' named entity 'THESE' named entity 'PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS' named entity 'BRIEF' named entity 'EUROPE' named entity 'DETERMINE' named entity 'EUROPEAN' named entity 'EQUINE ARTERITIS VIRUS' named entity 'PROTEINS' named entity 'GENOTYPES' named entity 'REPRESENT' named entity 'INDICATED' named entity 'CANADIAN' named entity 'VIRULENCE' named entity 'U.S.' named entity 'LACTATE DEHYDROGENASE-ELEVATING VIRUS' named entity 'MEMBERS' named entity 'PROPOSED' named entity 'DISTANTLY' named entity '100%' named entity 'REPORT' named entity 'PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS' named entity 'U.S.A.' named entity 'GENES' named entity 'NUCLEOCAPSID' named entity 'DISTINCT' named entity 'AMINO ACID SEQUENCES' named entity 'SEQUENCE IDENTITY' named entity 'ARTERIVIRUS' named entity 'CLONED' named entity 'RELATED' named entity 'MEMBRANE' named entity 'GROUP' named entity 'SIMILAR' named entity 'GROUPS' named entity 'KNOWN' named entity 'FELL' named entity 'ALIGNED' named entity 'INCLUDING' named entity 'THEIR' named entity 'ISOLATES' named entity 'EXTENT' named entity 'PROTEIN ' named entity 'BASIS' named entity 'TREES' named entity 'GENES' covid:arg/045ca16ba40806eadbfe0b8f420cb81bea7c10b5 named entity 'nucleocapsid' named entity 'protein' named entity 'virulence' named entity 'nucleocapsid' named entity 'U.S.' named entity 'amino acid sequences' named entity 'amino acid sequences' named entity 'genetic variation' named entity 'EAV' named entity 'genotypes' named entity 'ORF' named entity 'PRRSV' named entity 'algorithm' named entity 'silent mutation' named entity 'gene' named entity 'genetic variation' named entity 'maximum parsimony' named entity 'gene' named entity 'amino acid sequence identity' named entity 'sequence variation' named entity 'GenBank' named entity 'parsimonious' named entity 'Eastern equine encephalitis virus' named entity 'branch-and-bound' named entity 'motif'

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