About: Universal Mask Usage for Reduction of Respiratory Viral Infections After Stem Cell Transplant: A Prospective Trial

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About: Universal Mask Usage for Reduction of Respiratory Viral Infections After Stem Cell Transplant: A Prospective Trial Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Universal Mask Usage for Reduction of Respiratory Viral Infections After Stem Cell Transplant: A Prospective Trial
Creator	Broadwater, Gloria Corbet, Kelly Gasparetto, Cristina Hyslop, Terry Long, Gwynn Rizzieri, David Thomas, Samantha Chao, Nelson Horwitz, Mitchell Sullivan, Keith Sung, Anthony Sung, Julia
topic	covid:053157eb128be3d4084e10904eec6ddec309f9b2#this
Source	Medline; PMC
abstract	Background. Respiratory viral infections (RVIs) are frequent complications of hematopoietic stem cell transplant (HSCT). Surgical masks are a simple and inexpensive intervention that may reduce nosocomial spread. Methods. In this prospective single-center study, we instituted a universal surgical mask policy requiring all individuals with direct contact with HSCT patients to wear a surgical mask, regardless of symptoms or season. The primary endpoint was the incidence of RVIs in the mask period (2010–2014) compared with the premask period (2003–2009). Results. RVIs decreased from 10.3% (95/920 patients) in the premask period to 4.4% (40/911) in the mask period (P < .001). Significant decreases occurred after both allogeneic (64/378 [16.9%] to 24/289 [8.3%], P = .001) and autologous (31/542 [5.7%] to 16/622 [2.6%], P = .007) transplants. After adjusting for multiple covariates including season and year in a segmented longitudinal analysis, the decrease in RVIs remained significant, with risk of RVI of 0.4 in patients in the mask group compared with the premask group (0.19–0.85, P = .02). In contrast, no decrease was observed during this same period in an adjacent hematologic malignancy unit, which followed the same infection control practices except for the mask policy. The majority of this decrease was in parainfluenza virus 3 (PIV3) (8.3% to 2.2%, P < .001). Conclusions. Requiring all individuals with direct patient contact to wear a surgical mask is associated with a reduction in RVIs, particularly PIV3, during the most vulnerable period following HSCT.
has issue date	2016-08-01(xsd:dateTime)
bibo:doi	10.1093/cid/ciw451
bibo:pmid	27481873
has license	bronze-oa
sha1sum (hex)	053157eb128be3d4084e10904eec6ddec309f9b2
schema:url	https://doi.org/10.1093/cid/ciw451
resource representing a document's title	Universal Mask Usage for Reduction of Respiratory Viral Infections After Stem Cell Transplant: A Prospective Trial
has PubMed Central identifier	PMC5036914
has PubMed identifier	27481873
schema:publication	Clinical Infectious Diseases
resource representing a document's body	covid:053157eb128be3d4084e10904eec6ddec309f9b2#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/053157eb128be3d4084e10904eec6ddec309f9b2
is schema:about of	named entity 'HSCT' named entity 'complications' named entity 'reduce' named entity 'Transplant' covid:arg/053157eb128be3d4084e10904eec6ddec309f9b2 named entity 'frequent' named entity 'viral infections' named entity 'HSCT' named entity 'hematopoietic stem cell transplant' named entity 'hand hygiene' named entity 'infection control' named entity 'PCR-based' named entity 'HSCT' named entity 'Fisher exact test' named entity 'surgical masks' named entity 'influenza' named entity 'GVHD' named entity 'Stata' named entity 'correlation' named entity 'HSCT' named entity 'viral infection' named entity 'Duke Hospital' named entity 'surgical mask' named entity 'prophylaxis' named entity 'surgical mask' named entity '13.1' named entity 'PCR-based' named entity 'surgical mask' named entity 'SAS Institute' named entity 'effect size' named entity 'immunocompromised' named entity 'RSV' named entity 'RSV' named entity '12 January 2010' named entity 'sputum culture' named entity 'significant difference' named entity 'surgical mask' named entity 'medical record' named entity 'surgical mask' named entity 'segmented regression' named entity 'GVHD' named entity 'aerosol' named entity 'asymptomatic' named entity 'HSCT' named entity 'Wilcoxon rank-sum test' named entity 'infection control' named entity 'natural variation' named entity 'statistically significant' named entity 'HSCT' named entity 'GVHD' named entity 'respiratory symptoms' named entity 'influenza' named entity 'HSCT' named entity 'PCR' named entity 'bone marrow transplant' named entity 'College Station, Texas' named entity 'HSCT' named entity 'surgical mask' named entity 'Respiratory viral infections' named entity 'positive test' named entity 'hematopoietic stem cell transplant' named entity 'infection control' named entity 'virus' named entity 'HSCT' named entity 'asymptomatic' named entity 'HSCT' named entity 'chemotherapy' named entity 'HSCT'

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