About: Acute Cough in the Elderly: Aetiology, Diagnosis and Therapy

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Acute Cough in the Elderly: Aetiology, Diagnosis and Therapy
Creator	Kamath, Shankar Widdicombe, John
Source	Medline; PMC
abstract	Although the frequency of physician consultations and the sale of over-the-counter remedies establish the high prevalence of acute cough in the elderly, epidemiological studies have tended to be imprecise. However, respiratory tract infections in nose, larynx and/or bronchi, either viral or bacterial or both, are by far the commonest cause of acute cough. These are especially frequent and hazardous in the elderly, and community living and institutionalisation may aggravate this problem. A variety of viruses and bacteria have been incriminated, with rhinovirus, influenza and respiratory syncytial viruses, and Streptococcus pneumoniae, Haemophilus influenza and Bordetella pertussis being especially important. Viral infections can readily lead to community-acquired pneumonia. Successful diagnosis should point to successful treatment, and in this respect clinical examination and patient history are paramount, supplemented by chest X-ray, viral and bacterial culture and serological testing. Depending on the results of these tests, specific antibacterial therapy may be called for, although there is dispute as to the merits of antibacterial therapy in cases of uncertain diagnosis. Prevention and prophylaxis for influenza and S. pneumoniae infections are now commendably routine in the elderly, especially those in communities. Treatment, as well as the use of antibacterials, may also be directed against the inflammatory and infective processes in the airways. Non-specific antitussive therapy is common and usually highly desirable to prevent the adverse effects of repeated coughing. There have been few advances in antitussive therapy in recent years, opioids and dextromethorphan being the most commonly used agents; they act centrally on the brainstem, but also have a large placebo effect. However they work, they are much appreciated by patients and their partners. Moreover, striking advances in our understanding of the peripheral sensory and central nervous pathways of the cough reflex in recent years should soon lead to a new and more specific choice of agents to inhibit cough.
has issue date	2012-08-29(xsd:dateTime)
bibo:doi	10.2165/00002512-200421040-00003
bibo:pmid	15012170
has license	no-cc
sha1sum (hex)	0693ce44c8059f0c65a977fa97e2d86d581698c7
schema:url	https://doi.org/10.2165/00002512-200421040-00003
resource representing a document's title	Acute Cough in the Elderly: Aetiology, Diagnosis and Therapy
has PubMed Central identifier	PMC7100077
has PubMed identifier	15012170
schema:publication	Drugs Aging
resource representing a document's body	covid:0693ce44c8059f0c65a977fa97e2d86d581698c7#body_text
is schema:about of	named entity 'Diagnosis' named entity 'Therapy' named entity 'THERAPY' named entity 'ACUTE COUGH' named entity 'AETIOLOGY' named entity 'DIAGNOSIS' named entity 'ELDERLY' named entity 'respiratory syncytial virus' named entity 'tomography' named entity 'RSV' named entity 'URT' named entity 'trachea' named entity 'Cough' named entity 'coronavirus' named entity 'bacterial pathogens' named entity 'sensory receptors' named entity 'mexiletine' named entity 'idiopathic' named entity 'placebo effect' named entity 'M. catarrhalis' named entity 'CXR' named entity 'Monto' named entity 'patient history' named entity 'hydrocodone' named entity 'PND' named entity 'antibacterials' named entity 'Parkinson's disease' named entity 'coronavirus' named entity 'cough' named entity 'opioid receptors' named entity 'cough' named entity 'patient history' named entity 'Bronchodilators' named entity 'OTC' named entity 'Symptomatic treatment' named entity 'COPD' named entity 'influenza infection' named entity 'trachea' named entity 'cough' named entity 'cough' named entity 'mucosa' named entity 'cough' named entity 'rhinitis' named entity 'Cough' named entity 'influenza' named entity 'pneumonia' named entity 'influenza' named entity 'cough' named entity 'cough' named entity 'elderly patients' named entity 'virus' named entity 'URTI' named entity 'experimental animals' named entity 'cough' named entity 'methadone' named entity 'Antibacterials' named entity 'bacterial culture' named entity 'sore throat' named entity 'secretion' named entity 'lungs' named entity 'metabolites' named entity 'morbidity' named entity 'serotypes' named entity 'brainstem' named entity 'serological testing' named entity 'bacterial infection' named entity 'URT' named entity 'acute rhinitis' named entity 'cough' named entity 'cough' named entity 'respiratory tract' named entity 'experimental animals' named entity 'chronic cough' named entity 'cough' named entity 'coronavirus' named entity 'cough' named entity 'bronchitis' named entity 'Epidemiology' named entity 'fever' named entity 'placebo'

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