About: Epidemiological investigation and intergenerational clinical characteristics of 24 COVID-19 patients associated with supermarket cluster

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Epidemiological investigation and intergenerational clinical characteristics of 24 COVID-19 patients associated with supermarket cluster
Creator	Wu, Min Han, Jian Chen, Juan Tian, Hui Zhang, Lina Chang, Zhenqin Ning, Kang Tian, Suochen Wang, Yunxia Wu, Tiejun Xing, Junmin Zhang, Wenming Zhou, Guijie Zou, Xiuli Chen, Shuangfeng Liu, Mingxin Zhang, Xihong
source	MedRxiv
abstract	Objective: To analyze the epidemiological and intergenerational clinical characteristics of COVID-19 patients associated with cluster, so as to understand the rules of the patients associated with cluster of this outbreak and provide help for the prevention and control of COVID-19. Methods: All close contacts of the patient were screened since the first supermarket employee with COVID-19 was identified. A retrospective analysis was made on the epidemiological and clinical characteristics of the confirmed cases admitted to the designated hospitals for centralized treatment. The patients were divided into two groups according to the first generation (supermarket employees, group A) and the second or third generation (family members or friends of supermarket employees, group B), and the similarities and differences between the two groups were compared. Results: A total of 24 COVID-19 patients were diagnosed, with an average age of 48{+/-}1.73 years. The mean duration from onset to release form quarantine was 21.04{+/-}6.77 days, and the onset time was concentrated in 5-11 days after the first patient was diagnosed. Among all the patients, 23 patients were moderate, among which 7 patients (29.17%) were asymptomatic. Symptoms of symptomatic patients were cough (75.00%), low fever (62.50%), shortness of breath (41.67%), sore throat (25.00%), gastrointestinal symptoms (25.00%), fatigue (20.83%), etc. Biochemical examination on admission showed that the white blood cell count < 4.010x9/L (29.17%) and the lymphocyte count <1.1x109/L (58.33%). The lymphocyte count of 50.00% of the patients was [≤]0.6x109/L. On admission, chest CT showed pneumonia (100%) with bilateral infiltration (75.00%). Treatment: antiviral drug (100%), Chinese medicine (100%), common oxygen therapy (45.83%). There were 11 cases in group A (first generation, 11 cases) and 13 cases in group B (second generation, 11 cases; third generation, 2 cases). In group B, there were more males, from onset to admission later, more patients had underlying diseases, and more patients were treated with albumin (P<0.05). However, there was no statistical difference between the two groups in other clinical indicators, including the duration from onset to release form quarantine(P>0.05). There was no improvement in granulocyte count in all patients, as well as in groups A and B, between admission and release from quarantine(P>0.05). Conclusion: The clinical characteristics of COVID-19 patients associated with cluster were similar to those of other COVID-19 patients, but there were some special features. The severity of the disease was similar and there was intergenerational spread. There was no difference in clinical characteristics between generations. Asymptomatic infections occurred in a proportion of patients and could cause spread.
has issue date	2020-04-15(xsd:dateTime)
bibo:doi	10.1101/2020.04.11.20058891
has license	medrxiv
sha1sum (hex)	084e550529d93c2ade48cbac52d85daca81ef972
schema:url	https://doi.org/10.1101/2020.04.11.20058891
resource representing a document's title	Epidemiological investigation and intergenerational clinical characteristics of 24 COVID-19 patients associated with supermarket cluster
resource representing a document's body	covid:084e550529d93c2ade48cbac52d85daca81ef972#body_text
is schema:about of	named entity 'intergenerational' named entity 'patients' named entity 'supermarket' named entity 'clinical characteristics' named entity 'Epidemiological' named entity 'Wilcoxon rank-sum' named entity 'Chi-square test' named entity 'coronavirus' named entity 'quarantine' named entity 'respiratory tract' named entity 'standard deviations' named entity 'COVID-19' named entity 'National Health Commission' named entity 'COVID-19' named entity 'antiviral drugs' named entity 'fever' named entity 'granulocyte' named entity 'coronavirus' named entity 'antiviral drugs' named entity 'medRxiv' named entity 'virus' named entity 'epidemiological' named entity 'COVID-19' named entity 'COVID 19' named entity 'antibiotics' named entity 'COVID 19' named entity 'COVID-19' named entity 'sore throat' named entity 'COVID-19' named entity 'quarantine' named entity 'Asymptomatic infection' named entity 'Hubei' named entity 'Epidemiology' named entity 'oxygen therapy' named entity '3 generations' named entity 'COVID 19' named entity 'China' named entity 'antibiotics' named entity 'COVID-19' named entity 'pneumonia' named entity 'quarantine' named entity 'acupuncture' named entity 'diabetes' named entity '8 days' named entity 'COVID-19' named entity 'fever' named entity 'white blood cell' named entity 'quarantine' named entity 'Nasal Cannula' named entity 'COVID-19' named entity 'traditional Chinese medicine' named entity 'moxibustion' named entity 'quarantine' named entity 'Chinese medicine' named entity 'peer review' named entity 'Liaocheng' named entity 'RT-PCR' named entity 'TCM' named entity 'symptom' named entity 'COVID-19' named entity 'peer review' named entity 'lymphocyte' named entity 'National Administration of Traditional Chinese Medicine' named entity 'asymptomatic' named entity 'quarantine' named entity 'Middle East' named entity 'incubation period' named entity 'PSI' named entity 'Asymptomatic infections'

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