About: Exhaled nitric oxide and pulmonary complications after paediatric stem cell transplantation

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Exhaled nitric oxide and pulmonary complications after paediatric stem cell transplantation
Creator	Fazekas, T Lawitschka, A Peters, C Eickhoff, P Pötschger, U Knotek, B
Source	PMC
abstract	Pulmonary complications are major causes of morbidity and mortality after haematopoietic stem cell transplantation (HSCT). We hypothesise that elevated exhaled nitric oxide (FeNO) levels early after HSCT in children are predictive for pulmonary complications. The present prospective study included 30 children (age, 4–18 years) before HSCT. FeNO levels were evaluated 10 days before transplant, at day 0, day +28 and day +60 after HSCT. During the follow-up period until day +100, pulmonary complications and lung function were assessed. Before HSCT, the mean FeNO levels were comparable in children with or without post-transplant pulmonary complications. However, they differed at day 0 and day +28 with a mean of 7 (±1.95) and 13 (±3.44) ppb at day 0 and a mean of 13 (±3.44) and 14 (±3.57) ppb at day +28, respectively. Conclusion: Children with pulmonary complications after day +28 have higher mean FeNO levels 28 days after HSCT than children without later pulmonary complications. Therefore, FeNO could be an important diagnostic tool for hyperinflammatory response in bronchial epithelium after paediatric HSCT.
has issue date	2012-02-16(xsd:dateTime)
bibo:doi	10.1007/s00431-012-1692-x
bibo:pmid	22350283
has license	no-cc
sha1sum (hex)	096dd60c52a31f8a7dacbc5cbbe0d5f8cb1ace26
schema:url	https://doi.org/10.1007/s00431-012-1692-x
resource representing a document's title	Exhaled nitric oxide and pulmonary complications after paediatric stem cell transplantation
has PubMed Central identifier	PMC7102378
has PubMed identifier	22350283
schema:publication	Eur J Pediatr
resource representing a document's body	covid:096dd60c52a31f8a7dacbc5cbbe0d5f8cb1ace26#body_text
is schema:about of	named entity 'tool' named entity 'haematopoietic stem cell' named entity 'predictive' named entity 'HSCT' named entity 'CHILDREN' named entity 'PULMONARY COMPLICATIONS' named entity 'ASSESSED' named entity 'EARLY' named entity 'DAYS' named entity 'HSCT' named entity 'DAY' named entity 'day' named entity 'During' named entity 'day' named entity 'HSCT' named entity 'ppb' named entity 'assessed' named entity 'transplantation' named entity 'mortality' named entity 'stem cell' named entity 'epithelium' named entity 'diagnostic tool' named entity 'ppb' named entity 'pulmonary complications' named entity 'paediatric' named entity 'Pulmonary complications' named entity 'pulmonary complications' named entity 'HSCT' named entity 'pulmonary complications' named entity 'pulmonary complications' named entity 'corticosteroids' named entity 'pulmonary complications' named entity 'GvHD' named entity 'acute lymphoblastic leukaemia' named entity 'pulmonary complications' named entity 'TLC' named entity 'GvHD' named entity 'respiratory symptoms' named entity 'HSCT' named entity 'bronchial inflammation' named entity 'epithelium' named entity 'chest X-rays' named entity 'CD3+' named entity 'Mycoses' named entity 'HSCT' named entity 'HSCT' named entity 'lung function' named entity 'flow chart' named entity 'pulmonary complications' named entity 'Chicago' named entity 'epithelium' named entity 'inducible nitric oxide synthase' named entity 'correlation' named entity 'paediatric' named entity 'pulmonary complications' named entity 'HSCT' named entity 'GvHD' named entity 'underlying diseases' named entity 'IgE' named entity 'HSCT' named entity 'pulmonary infections' named entity 'HSCT' named entity 'ppb' named entity 'HSCT' named entity 'aetiology' named entity 'ppb' named entity 'correlation' named entity 'HSCT' named entity 'upregulated' named entity 'lung function' named entity 'respiratory impairment' named entity 'busulfan' named entity 'immunosuppressed' named entity 'atopy' named entity 'prednisone' named entity 'Declaration of Helsinki'

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