About: Viral sepsis is a complication in patients with Novel Corona Virus Disease (COVID-19)

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About: Viral sepsis is a complication in patients with Novel Corona Virus Disease (COVID-19) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viral sepsis is a complication in patients with Novel Corona Virus Disease (COVID-19)
Creator	Zhang, Jing Wang, Qiang Liu, Di Wang, Jun Chen, Yong Deng, Jin Zeng, Ling Cui, Li Jiang, Cai, Qingli Cn;, Jianxin Gan, Lebin Jiang, Jianxin Shen, Feng Sun, Jiali Sun, Jianhui Zhang, Huacai
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: Until June 23th 2020, 9,195,635 laboratory-confirmed cases of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection have been reported worldwide, including 473,127 deaths. Bacterial infection is the main cause of sepsis, however, sepsis caused by virus is often ignored. Increased awareness, early recognition of viral sepsis, rapid administration of appropriate antiviral drugs, and urgent treatment can significantly reduce deaths of viral sepsis. OBJECTIVES: Given the rapid global spread of novel Corona Virus Disease (COVID-19), coupled with the high rate of missed diagnosis of viral sepsis caused by SARS-CoV-2 infection, it is urgent to evaluate the multiple organ failure score and viral sepsis in COVID-19 patients, so as to determine the clinical characteristics of viral sepsis more accurately and reveal the risk factors related to mortality. METHODS: Here we provide a full description of three cases of viral sepsis and subsequent multiple organ dysfunction (MODS) caused by SARS-CoV-2 infection imported to Guiyang from Wuhan. RESULTS: We analyzed complete laboratory examination, imaging data and treatment methods for the patients and assessed Sepsis-related Organ Failure Assessment score (SOFA score) and Multiple organ dysfunction scores (MOD score) daily, aimed to elucidate the clinical feature of viral sepsis and MODS and to attract enough attention by clinicians. CONCLUSIONS: Therefore, we strongly suggest to daily evaluate SOFA score and MOD score in severe and critically-ill COVID-19 patients, so as to early diagnose and prevention of sepsis and MODS. Given the rapid global spread of novel Corona Virus Disease (COVID-19), coupled with the high rate of missed diagnosis of viral sepsis caused by SARS-CoV-2 infection, it is urgent to evaluate the multiple organ failure score and viral sepsis in COVID-19 patients, so as to determine the clinical characteristics of viral sepsis more accurately and reveal the risk factors related to mortality. Here we provide a full description of three cases of viral sepsis and subsequent multiple organ dysfunction (MODS) caused by SARS-CoV-2 infection imported to Guiyang from Wuhan. We analyzed complete laboratory examination, imaging data and treatment methods for the patients and assessed Sepsis-related Organ Failure Assessment score (SOFA score) and Multiple organ dysfunction scores (MOD score) daily, aimed to elucidate the clinical feature of viral sepsis and MODS and to attract enough attention by clinicians. Therefore, we strongly suggest to daily evaluate SOFA score and MOD score in severe and critically-ill COVID-19 patients, so as to early diagnose and prevention of sepsis and MODS.
has issue date	2020-07-24(xsd:dateTime)
bibo:doi	10.1016/j.medidd.2020.100057
bibo:pmid	32838292
has license	no-cc
sha1sum (hex)	096de5f38ec665b18c430bd0d10898be394975fb
schema:url	https://doi.org/10.1016/j.medidd.2020.100057
resource representing a document's title	Viral sepsis is a complication in patients with Novel Corona Virus Disease (COVID-19)
has PubMed Central identifier	PMC7378467
has PubMed identifier	32838292
schema:publication	Med Drug Discov
resource representing a document's body	covid:096de5f38ec665b18c430bd0d10898be394975fb#body_text
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