About: Detection of lung hypoperfusion in Covid-19 patients during recovery by digital imaging quantification

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About: Detection of lung hypoperfusion in Covid-19 patients during recovery by digital imaging quantification Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Detection of lung hypoperfusion in Covid-19 patients during recovery by digital imaging quantification
Creator	Remuzzi, Andrea Remuzzi, Patelli, Gianluigi Besana, Francesca Codazzi, Fabiana »more»
source	MedRxiv
abstract	Purpose. A large number of patients affected by the SARS-Cov-2 virus worldwide undergo recovery of symptoms in about one month. Among these patients, the healing process is still under observation, with some patients in need of careful clinical monitoring. While the radiological findings have been shown to regress almost completely, little knowledge is available at the moment about other complications in the lung and in other organs. We then investigated the lung perfusion conditions in patients affected by COVID- 19 during recovery. Method. We retrospectively studied 20 patients, from 14 to 60 days after resolution of the COVID-19 symptoms, using chest CT. In a subgroup of 5 patients contrasted CT was used. Beside normal radiological evaluation of lung tissue, perfusion conditions were evaluated by digital image processing in the lung volume automatically segmented. Results. Pulmonary lung evaluation showed that COVID-19 pneumonia almost completely regressed, with mild focal areas affected by fibrous stripes. In patients that reported dyspnea, lung CT showed complete resolution of interstitial changes. Quantification of lung perfusion condition by contrasted CT, showed that dyspnea in 3 patients was associated with areas of hypoperfusion, while in 2 patients not reporting dyspnea perfusion conditions were comparable to normal controls. Conclusions. Although we obtained preliminary data, this is the first report on quantitative evaluation of hypoperfused lung tissue detected in recovering COVID-19 patients. These results suggest the need to further investigate these patients and to redefine the role of CT evaluation for diagnostic purposes as well as for evaluation of potential treatments.
has issue date	2020-06-03(xsd:dateTime)
bibo:doi	10.1101/2020.05.29.20117143
has license	medrxiv
sha1sum (hex)	09a6fad7371956e64e6f1c58d848268c84948557
schema:url	https://doi.org/10.1101/2020.05.29.20117143
resource representing a document's title	Detection of lung hypoperfusion in Covid-19 patients during recovery by digital imaging quantification
resource representing a document's body	covid:09a6fad7371956e64e6f1c58d848268c84948557#body_text
is schema:about of	named entity 'COVID-19' named entity 'patients' named entity 'regress' named entity 'hypoperfusion' named entity 'OBSERVATION' »more»

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