About: Human metapneumovirus in paediatric patients

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Human metapneumovirus in paediatric patients
Creator	Esposito, S Principi, N Bosis, S
Source	Elsevier; Medline; PMC
abstract	Acute respiratory tract infections (ARTIs) are a leading cause of morbidity and mortality in children worldwide, but the aetiology of many ARTIs is still unknown. In 2001, researchers in The Netherlands reported the discovery of a previously unidentified pathogen called human metapneumovirus (hMPV). Since its initial description, hMPV has been associated with ARTI in Europe (Italy, France, Spain, the UK, Germany, Denmark, Finland and Norway), America (the USA, Canada, Argentina and Brazil), Asia (India, Japan, China and Singapore), Australia and South Africa in individuals of all ages. The incidence of infection varies from 1.5% to 25%, indicating that hMPV is a ubiquitous virus with a worldwide distribution. hMPV seems to play an important role as a cause of paediatric upper and lower respiratory tract infection, with similar, but not identical, epidemiological and clinical features to those of respiratory syncytial virus and influenza virus. Moreover, the socio-economic impact of hMPV-infected children on their families seems to be considerable, which suggests that, like influenza virus, hMPV infection may be a substantial public health problem for the community. It may be associated with significant morbidity and mortality in pre-term infants and children with underlying clinical conditions, although more adequately controlled studies are needed to confirm its importance in such patients. Many fundamental questions concerning the pathogenesis of hMPV disease and the host's specific immune response remain to be answered. Further studies are also required to properly define hMPV diagnosis, treatment and prevention strategies.
has issue date	2014-12-12(xsd:dateTime)
bibo:doi	10.1111/j.1469-0691.2005.01325.x
bibo:pmid	16524405
has license	no-cc
sha1sum (hex)	0a8d9887e378df263878873a4b7be141aa224b42
schema:url	https://doi.org/10.1111/j.1469-0691.2005.01325.x
resource representing a document's title	Human metapneumovirus in paediatric patients
has PubMed Central identifier	PMC7128939
has PubMed identifier	16524405
schema:publication	Clin Microbiol Infect
resource representing a document's body	covid:0a8d9887e378df263878873a4b7be141aa224b42#body_text
is schema:about of	named entity 'researchers' named entity 'REPORTED' named entity 'DISCOVERY' named entity 'PATHOGEN' named entity 'MORBIDITY AND MORTALITY' named entity 'UNIDENTIFIED' named entity 'ACUTE' named entity 'PATIENTS' named entity 'HUMAN METAPNEUMOVIRUS' named entity 'DESCRIPTION' named entity 'CAUSE' named entity 'AETIOLOGY' named entity 'EUROPE' named entity 'WORLDWIDE' named entity 'ARTI' named entity 'LEADING' named entity 'INITIAL' named entity 'ITS' named entity 'RESPIRATORY TRACT INFECTIONS' named entity 'HUMAN METAPNEUMOVIRUS' named entity 'PREVIOUSLY' named entity 'ASSOCIATED WITH' named entity 'BUT' named entity 'THE NETHERLANDS' named entity 'UNKNOWN' named entity 'CHILDREN' named entity 'PAEDIATRIC' named entity 'RESEARCHERS' named entity '2001' named entity 'ARTIs' named entity 'human metapneumovirus' named entity 'Netherlands' named entity 'patients' named entity 'The Netherlands' named entity 'hMPV' named entity 'hMPV' named entity 'Italy' named entity 'alveolar' named entity 'influenza viruses' named entity 'clinical studies' named entity 'seroprevalence' named entity 'virus infections' named entity 'Asia' named entity 'polymerase' named entity 'serological surveys' named entity 'acute episode' named entity 'clinical diagnosis' named entity 'antiviral activity' named entity 'influenza viruses' named entity 'term infant' named entity 'recombinant' named entity 'hMPV' named entity 'immune response' named entity 'enlarged liver' named entity 'Netherlands' named entity 'respiratory tract infections' named entity 'epithelial cell' named entity 'parainfluenza' named entity 'extracorporeal membrane oxygenation' named entity 'pneumoviruses' named entity 'myofibroblast' named entity 'lower respiratory tract infections' named entity 'bronchiolitis' named entity 'bronchitis' named entity 'infection' named entity 'cell lines' named entity 'influenza' named entity 'specific immune response' named entity 'hMPV' named entity 'virus' named entity 'Germany' named entity 'squamous metaplasia' named entity 'Metapneumovirus' named entity 'RNA' named entity 'RNA virus' named entity 'RSV' named entity 'acute respiratory infection' named entity 'influenza' named entity 'human infection'

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