About: A cross-sectional comparison of epidemiological and clinical features of patients with coronavirus disease (COVID-19) in Wuhan and outside Wuhan, China

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About: A cross-sectional comparison of epidemiological and clinical features of patients with coronavirus disease (COVID-19) in Wuhan and outside Wuhan, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A cross-sectional comparison of epidemiological and clinical features of patients with coronavirus disease (COVID-19) in Wuhan and outside Wuhan, China
Creator	Liu, Jing Chen, Junfeng Peng, Liang Li, Xuejun Cao, Huijuan Cao, Hong Gao, Zhiliang Jie, Yusheng Chen, Dabiao Huang, Zhanlian Lei, Ziying Xu, Wenxiong Dai, Xiaoling Guo, Xiaoyan He, Jian-Rong Lin, Bing-Liang Zhu, Jianyun
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: Coronavirus disease 2019 (COVID-19) has spread outside the initial epicenter of Wuhan. We compared cases in Guangzhou and Wuhan to illustrate potential changes in pathogenicity and epidemiological characteristics as the epidemic has progressed. METHODS: We studied 20 patients admitted to the Third Affiliated Hospital of Sun Yat-Sen University in Guangzhou, China from January 22 to February 12, 2020. Data were extracted from medical records. These cases were compared with the 99 cases, previously published in Lancet, from Wuhan Jinyintan Hospital from January 1 to January 20, 2020. RESULTS: Guangzhou patients were younger and had better prognosis than Wuhan patients. The Wuhan patients were more likely to be admitted to the ICU (23% vs 5%) and had a higher mortality rate (11% vs 0%). Cases in Guangzhou tended to be more community clustered. Diarrhea and vomiting were more common among Guangzhou patients and SARS-CoV-2 RNA was found in feces. Fecal SARA-CoV-2 RNA remained positive when nasopharyngeal swabs turned negative in some patients. CONCLUSIONS: This study indicates possible diminishing virulence of the virus in the process of transmission. Yet persistent positive RNA in feces after negative nasopharyngeal swabs suggests a possible prolonged transmission period that challenges current quarantine practices.
has issue date	2020-04-09(xsd:dateTime)
bibo:doi	10.1016/j.tmaid.2020.101664
bibo:pmid	32278758
has license	no-cc
sha1sum (hex)	0b5edd2e409c245c0934d4e7cb2d04f1c1fe1731
schema:url	https://doi.org/10.1016/j.tmaid.2020.101664
resource representing a document's title	A cross-sectional comparison of epidemiological and clinical features of patients with coronavirus disease (COVID-19) in Wuhan and outside Wuhan, China
has PubMed Central identifier	PMC7194579
has PubMed identifier	32278758
schema:publication	Travel Med Infect Dis
resource representing a document's body	covid:0b5edd2e409c245c0934d4e7cb2d04f1c1fe1731#body_text
is schema:about of	named entity 'ICU' named entity 'quarantine' named entity 'Wuhan' named entity 'COVID-19' named entity 'STUDY' named entity 'DIMINISHING' named entity 'PROCESS' named entity 'ADMITTED TO' named entity 'PROGNOSIS' covid:arg/0b5edd2e409c245c0934d4e7cb2d04f1c1fe1731 named entity 'remained' named entity 'Diarrhea' named entity 'positive' named entity 'younger' named entity 'patients' named entity 'Wuhan' named entity 'positive' named entity 'transmission' named entity 'RNA' named entity 'Wuhan' named entity 'patients' named entity 'Results' named entity 'transmission' named entity 'RNA' named entity 'RNA' named entity 'Guangzhou' named entity 'Wuhan' named entity 'Diarrhea' named entity 'nasopharyngeal swabs' named entity 'SARS-CoV-2' named entity 'cross-sectional' named entity 'COVID' named entity 'Middle East respiratory syndrome coronavirus' named entity 'ground-glass opacities' named entity 'myalgia' named entity 'airway' named entity 'Guangzhou' named entity 'Guangzhou' named entity 'COVID' named entity 'IBM' named entity 'Guangdong' named entity 'feces' named entity 'antiviral therapy' named entity 'creatine kinase' named entity 'Wuhan' named entity 'liver' named entity 'pneumonia' named entity 'real-time RT-PCR' named entity 'nucleocapsid protein' named entity 'gastrointestinal symptoms' named entity 'nasopharyngeal swab' named entity 'RNA' named entity 'Coronaviruses' named entity 'COVID-2019' named entity 'Wuhan' named entity 'pathogenicity' named entity 'Guangdong' named entity 'feces' named entity 'SARS-CoV' named entity 'CRP' named entity 'COVID' named entity 'Wuhan' named entity 'Wuhan' named entity 'virus' named entity 'COVID'

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