About: Type I IFN immunoprofiling in COVID-19 patients

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About: Type I IFN immunoprofiling in COVID-19 patients Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Type I IFN immunoprofiling in COVID-19 patients
Creator	Lina, Bruno Bitker, Laurent Richard, Jean-Christophe Gaymard, Alexandre Belot, Alexandre Perret, Magali Brengel-Pesce, Karen Trouillet-Assant, Sophie Belot, Hospitalier, Centre Mezidi, Mezidi, Mehdi Pons, Sylvie Pr, Alexandre Study, Hcl Sud, Lyon Viel, Sebastien Villard, Marine
Source	Elsevier; Medline; PMC
abstract	COVID patients in ICU present a high mortality rate and immunoprofiling reveals heterogeneous IFN-α2 production with about 20% of critically-ill patients unable to produce IFN-α2, highlighting the immune response heterogeneity and opening avenues for targeted therapies.
has issue date	2020-04-29(xsd:dateTime)
bibo:doi	10.1016/j.jaci.2020.04.029
bibo:pmid	32360285
has license	els-covid
sha1sum (hex)	0b691903cee3f26d6d36351604ed1337d8c12bdb
schema:url	https://doi.org/10.1016/j.jaci.2020.04.029
resource representing a document's title	Type I IFN immunoprofiling in COVID-19 patients
has PubMed Central identifier	PMC7189845
has PubMed identifier	32360285
schema:publication	The Journal of allergy and clinical immunology
resource representing a document's body	covid:0b691903cee3f26d6d36351604ed1337d8c12bdb#body_text
is schema:about of	named entity 'patients' named entity 'cytokine' named entity 'JAK-STAT signaling' named entity '1.000' named entity 'Type I interferons' named entity 'BMI' named entity 'immune response' named entity 'infection' named entity 'Smokers' named entity 'invasive mechanical ventilation' named entity 'infection' named entity 'multiplexed' named entity 'IFN' named entity 'ICU' named entity 'Haute Savoie' named entity 'exact test' named entity 'COVID-19' named entity 'Interleukin 6' named entity 'ICU' named entity 'IL-6' named entity 'plasma' named entity 'SARS-CoV-2' named entity 'CRP' named entity 'asymptomatic carriage' named entity 'Clinical characteristics' named entity 'IFN-β' named entity 'respiratory failure' named entity 'antiviral' named entity 'viral strain' named entity 'symptom' named entity 'cytokines' named entity 'assay' named entity 'Interferon' named entity 'Interleukin' named entity 'intensive care unit' named entity 'pneumonia' named entity 'mice' named entity 'co-infection' named entity 'symptom' named entity 'SARS-COV-2' named entity 'Severe acute respiratory syndrome coronavirus 2' named entity 'IL-6' named entity 'PhD' named entity 'Intensive Care Unit' named entity 'infection' named entity 'France' named entity 'Viral load' named entity 'targeted therapies' named entity 'IFN-γ' named entity 'innate immune' named entity 'risk factors' named entity 'intensive care' named entity 'C-Reactive Protein' named entity 'assay' named entity 'ICU' named entity 'COVID' named entity 'ICU' named entity 'Viral' named entity 'ICU' named entity 'PhD' named entity 'proof of concept' named entity 'immunotherapies' named entity 'CRP' named entity 'Body Mass Index'

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