About: Prospective case-control analysis of the aetiologies of acute undifferentiated fever in Vietnam

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Prospective case-control analysis of the aetiologies of acute undifferentiated fever in Vietnam Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Prospective case-control analysis of the aetiologies of acute undifferentiated fever in Vietnam
Creator	Raoult, Didier Parola, Philippe Abat, Cédric Cao, Thanh-Van Chung, Hai Le, Viet-Nho Le-Viet, Nhiem Phan, Duc-Tuan Phan, Quang-Duong
Source	Medline; PMC
abstract	Acute undifferentiated fever (AUF) is frequently observed in tropical settings, but diagnosing the cause of AUF is often a challenge for local physicians and the physicians treating returning travellers. We conducted a case-control study in central Vietnam in 2016. A total of 378 febrile adult patients (AUFs) with a fever for ≤21 days, no evidence of localized infection and negative screening tests for dengue and malaria, and 384 afebrile adult patients (Controls) were prospectively enrolled. Whole blood, plasma, eschar swab, throat swab and urine specimens were collected and analysed. Quantitative PCR and RT-PCR were used to test for 55 bacteria, viruses and their subtypes. Serological tests were also used to test for rickettsial agents. The most common aetiology was influenza virus (20.9% in AUFs vs. 0% in Controls), followed by rickettsial agents (mainly Orientia tsutsugamushi and Rickettsia typhi) (10.8% vs. 0.3%), dengue virus (7.7% vs. 0.5%), Leptospira (4.8% vs. 0.8%), adenovirus (4.8% vs. 1.0%), and enterovirus (2.1% vs. 0%) (p < .05). The real proportion of dengue in AUF cases was underestimated because patients with dengue-positive rapid diagnosis tests were excluded from the study. The emerging agent Rickettsia felis, which had not been previously observed in Vietnam, was detected in this study. In total, 216 patients (57.1%) were given causative diagnoses, comprising 143 (66.2%) monoinfections and 73 (33.8%) coinfections. The infections caused by these agents should be considered in clinical practice and further studies. Additionally, agents susceptible to doxycycline were detected in 15.6% of AUFs; thus, this drug should be included in the panel used to treat AUF patients.
has issue date	2019-03-04(xsd:dateTime)
bibo:doi	10.1080/22221751.2019.1580539
bibo:pmid	30866787
has license	cc-by
sha1sum (hex)	0b9583908e91f87840a0f844e7c4ebb546482c50
schema:url	https://doi.org/10.1080/22221751.2019.1580539
resource representing a document's title	Prospective case-control analysis of the aetiologies of acute undifferentiated fever in Vietnam
has PubMed Central identifier	PMC6455186
has PubMed identifier	30866787
schema:publication	Emerg Microbes Infect
resource representing a document's body	covid:0b9583908e91f87840a0f844e7c4ebb546482c50#body_text
is schema:about of	named entity 'AFEBRILE' named entity 'INCLUDED' named entity 'WHOLE BLOOD' named entity 'OBSERVED' named entity 'DENGUE' named entity 'RICKETTSIA TYPHI' named entity '0.5' named entity 'FREQUENTLY' named entity 'CHALLENGE' named entity 'FOLLOWED BY' named entity 'PREVIOUSLY' named entity 'AETIOLOGY' named entity 'NO EVIDENCE OF' named entity 'AGENT' named entity 'DOXYCYCLINE' named entity 'TO TEST' named entity 'THEIR' named entity 'CENTRAL' named entity 'FEVER' named entity 'DENGUE VIRUS' named entity 'CONSIDERED' named entity 'INFLUENZA VIRUS' named entity 'BUT' named entity 'ESCHAR' named entity 'UNDIFFERENTIATED' named entity 'ADENOVIRUS' named entity 'EXCLUDED' named entity 'PROSPECTIVE' named entity 'FEVER' named entity 'influenza' named entity 'Whole blood' named entity 'Acute' named entity 'dengue virus' named entity 'test' named entity 'case-control' covid:arg/0b9583908e91f87840a0f844e7c4ebb546482c50 named entity 'ANALYSIS' named entity 'ADULT' named entity 'SCREENING TESTS' named entity 'SEROLOGICAL TESTS' named entity 'COLLECTED' named entity 'VIETNAM' named entity 'CAUSE' named entity '143' named entity 'DIAGNOSES' named entity 'LOCAL' named entity '0.8' named entity 'FEBRILE' named entity 'PHYSICIANS' named entity 'PLASMA' named entity 'DIAGNOSING' named entity 'URINE' named entity 'PROPORTION' named entity 'SPECIMENS' named entity 'QUANTITATIVE PCR' named entity 'TESTS' named entity 'INFECTIONS' named entity 'PANEL' named entity 'TROPICAL' named entity 'STUDIES' named entity 'MALARIA' named entity 'RICKETTSIA FELIS' named entity 'CASE-CONTROL STUDY' named entity 'TREATING' named entity 'SWAB' named entity 'ACUTE' named entity 'CASE-CONTROL' named entity 'VIRUSES' named entity 'LOCALIZED INFECTION' named entity 'STUDY' named entity 'RAPID DIAGNOSIS' named entity 'TOTAL' named entity 'LEPTOSPIRA'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software