About: Homotypic and heterotypic serum and milk antibody to rotavirus in normal, infected and vaccinated horses

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Homotypic and heterotypic serum and milk antibody to rotavirus in normal, infected and vaccinated horses
Creator	Snodgrass, D Browning, G Chalmers, R Fitzgerald, T Sale, C
Source	PMC
abstract	The homotypic and heterotypic antibody response to rotavirus was determined in three pony mares and their foals. The normal concentrations of anti-rotavirus antibodies in mares ‘milk and mares’ and foals′ serum over the first 10 weeks post-partum were measured using IgA, IgG and rotavirus sero-type-specific enzyme linked immunosorbent assays. Experimental infection of the foals with serotype 3 equine rotavirus produced a rapid, serotype-specific response which peaked 10 days after infection and a slower heterotypic response which peaked 32 days later. In contrast, vaccination of the mares with an inactivated, adjuvanted serotype 6 bovine rotavirus produced a heterotypic response similar to that of the homotypic response in both serum and milk, although the predominant response in serum was IgG, while in milk it was IgA. These results suggest that non serotype-restricted passive protection of foals against rotavirus may be achieved by parenteral vaccination of mares.
has issue date	2002-11-05(xsd:dateTime)
bibo:doi	10.1016/0378-1135(91)90150-e
bibo:pmid	1715620
has license	no-cc
sha1sum (hex)	0bc2460ee034e47cef4b23f740d50d70937cda6a
schema:url	https://doi.org/10.1016/0378-1135%2891%2990150-e
resource representing a document's title	Homotypic and heterotypic serum and milk antibody to rotavirus in normal, infected and vaccinated horses
has PubMed Central identifier	PMC7117508
has PubMed identifier	1715620
schema:publication	Vet Microbiol
resource representing a document's body	covid:0bc2460ee034e47cef4b23f740d50d70937cda6a#body_text
is schema:about of	covid:arg/0bc2460ee034e47cef4b23f740d50d70937cda6a named entity 'VACCINATED' named entity 'NORMAL' named entity 'INFECTED' named entity '244' named entity 'ANTIBODY' named entity 'VET' named entity 'BROWNING' named entity 'MILK' named entity 'INFECTED' named entity 'ROTAVIRUS' named entity 'VACCINATED' named entity 'HORSES' named entity 'ANTIBODY' named entity 'SALE' named entity 'FITZGERALD' named entity 'H.%' named entity 'SERUM' named entity 'NORMAL' named entity 'MILK' named entity 'SERUM' named entity 'HORSES' named entity 'ROTAVIRUS' named entity 'Microbiol.' named entity 'milk' named entity 'antibody' named entity 'rotavirus' named entity 'milk' named entity 'inoculation' named entity 'vaccination' named entity 'antibody titres' named entity 'homologous' named entity 'Rotavirus' named entity 'pathogens' named entity 'infection' named entity 'diluent' named entity 'rotavirus' named entity 'rotavirus' named entity 'sera' named entity 'incubation' named entity 'IgG' named entity 'lysate' named entity 'negative control' named entity 'post partum' named entity 'epitope' named entity 'foetal calf serum' named entity 'infection' named entity '37 °C' named entity 'serum' named entity 'milk' named entity 'post-partum' named entity 'mares' named entity 'infection' named entity 'milk' named entity 'udder' named entity 'mammary gland' named entity 'antigens' named entity 'lactation' named entity 'exponential regression' named entity 'VP6' named entity 'pH 9' named entity 'antibody' named entity 'intramuscular' named entity 'serotype' named entity 'rotavirus' named entity 'rotavirus infections' named entity 'IgA' named entity 'Mares' named entity 'epitope' named entity 'cross-reactive' named entity 'capsid protein' named entity 'antibody' named entity 'milk' named entity 'seropositive' named entity 'serotype' named entity 'antibody response' named entity 'milk'

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