About: Antifragility and Tinkering in Biology (and in Business) Flexibility Provides an Efficient Epigenetic Way to Manage Risk

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About: Antifragility and Tinkering in Biology (and in Business) Flexibility Provides an Efficient Epigenetic Way to Manage Risk Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Antifragility and Tinkering in Biology (and in Business) Flexibility Provides an Efficient Epigenetic Way to Manage Risk
Creator	Danchin, Antoine Noria, Stanislas Binder, Philippe
Source	Medline; PMC
abstract	The notion of antifragility, an attribute of systems that makes them thrive under variable conditions, has recently been proposed by Nassim Taleb in a business context. This idea requires the ability of such systems to ‘tinker’, i.e., to creatively respond to changes in their environment. A fairly obvious example of this is natural selection-driven evolution. In this ubiquitous process, an original entity, challenged by an ever-changing environment, creates variants that evolve into novel entities. Analyzing functions that are essential during stationary-state life yield examples of entities that may be antifragile. One such example is proteins with flexible regions that can undergo functional alteration of their side residues or backbone and thus implement the tinkering that leads to antifragility. This in-built property of the cell chassis must be taken into account when considering construction of cell factories driven by engineering principles.
has issue date	2011-11-29(xsd:dateTime)
bibo:doi	10.3390/genes2040998
bibo:pmid	24710302
has license	cc-by
sha1sum (hex)	0be7b06a39aa31b27514a501ebdd477f42b0919a
schema:url	https://doi.org/10.3390/genes2040998
resource representing a document's title	Antifragility and Tinkering in Biology (and in Business) Flexibility Provides an Efficient Epigenetic Way to Manage Risk
has PubMed Central identifier	PMC3927596
has PubMed identifier	24710302
schema:publication	Genes (Basel)
resource representing a document's body	covid:0be7b06a39aa31b27514a501ebdd477f42b0919a#body_text
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