About: Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses
Creator	Amatore, Donatella Bisignano, Benedetta Botta, Giorgia Garozzo, Adriana Nencioni, Lucia Saladino, Raffaele Timpanaro, Rossella Palamara, Anna Mattia Bizzarri, Bruno
topic	covid:0c377dd7decb2c054f500adceb434c1aeb573434#this
Source	Elsevier; Medline; PMC
abstract	Abstract Hydroxytyrosol and dihydrocaffeoyl catechols with lipophilic properties have been synthesized in high yield using tyrosinase immobilized on multi-walled carbon nanotubes by the Layer-by-Layer technique. All synthesized catechols were evaluated against a large panel of DNA and RNA viruses, including Poliovirus type 1, Echovirus type 9, Herpes simplex virus type 1 (HSV-1), Herpes simplex virus type 2 (HSV-2), Coxsackievirus type B3 (Cox B3), Adenovirus type 2 and type 5 and Cytomegalovirus (CMV). A significant antiviral activity was observed in the inhibition of HSV-1, HSV-2, Cox B3 and CMV. The mechanism of action of the most active dihydrocaffeoyl derivative was investigated against a model of HSV-1 infection.
has issue date	2015-09-01(xsd:dateTime)
bibo:doi	10.1016/j.bmc.2015.07.061
bibo:pmid	26260341
has license	els-covid
sha1sum (hex)	0c377dd7decb2c054f500adceb434c1aeb573434
schema:url	https://doi.org/10.1016/j.bmc.2015.07.061
resource representing a document's title	Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses
has PubMed Central identifier	PMC7125559
has PubMed identifier	26260341
schema:publication	Bioorganic & Medicinal Chemistry
resource representing a document's body	covid:0c377dd7decb2c054f500adceb434c1aeb573434#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/0c377dd7decb2c054f500adceb434c1aeb573434
is schema:about of	named entity 'SUPPORTED' named entity 'catechols' named entity 'model' named entity 'observed' named entity 'investigated' named entity 'inhibition' named entity 'catechols' named entity 'tyrosinase' named entity 'ANTIVIRAL ACTIVITY' named entity 'DNA' named entity 'COXSACKIEVIRUS' named entity 'MECHANISM OF ACTION' named entity 'DNA' named entity 'MULTI-WALLED CARBON NANOTUBES' named entity 'MODEL OF' named entity 'OBSERVED' named entity 'HAVE' named entity 'ECHOVIRUS TYPE 9' named entity 'HIGH YIELD' named entity 'LARGE' named entity 'USING' named entity 'HERPES SIMPLEX VIRUS TYPE 1' covid:arg/0c377dd7decb2c054f500adceb434c1aeb573434 named entity 'TYPE 5' named entity 'LIPOPHILIC' named entity 'INCLUDING' named entity 'HSV-2' named entity 'SYNTHESIS' named entity 'TYROSINASE' named entity 'CATECHOLS' named entity 'RNA VIRUSES' named entity 'CARBON NANOTUBES' named entity 'CYTOMEGALOVIRUS' named entity 'PANEL' named entity 'COX' named entity 'POLIOVIRUS TYPE 1' named entity 'HSV-1' named entity 'TECHNIQUE' named entity 'CATECHOLS' named entity 'HERPES SIMPLEX VIRUS TYPE 2' named entity 'TYPE' named entity 'ACTIVE' named entity 'LAYER' named entity 'ANTIVIRAL ACTIVITY' named entity 'HYDROXYTYROSOL' named entity 'DERIVATIVE' named entity 'ADENOVIRUS TYPE 2' named entity 'INVESTIGATED' named entity 'HYDROXYTYROSOL' named entity 'INHIBITION' named entity 'LIPOPHILIC' named entity 'HSV-1 INFECTION' named entity 'RNA VIRUSES' named entity 'CMV' named entity 'PROPERTIES' named entity 'SYNTHESIZED' named entity 'TYROSINASE' named entity 'SIGNIFICANT' named entity 'EVALUATED' named entity 'carbon nanotubes' named entity 'virus' named entity 'DNA' named entity 'immobilized' named entity 'Adenovirus' named entity 'antiviral' named entity 'type 2' named entity 'tyrosinase' named entity 'catechols' named entity 'Coxsackievirus' named entity 'tyrosinase' named entity 'antiviral activity'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software