About: Adenoviral vector-based strategies against infectious disease and cancer

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Adenoviral vector-based strategies against infectious disease and cancer
Creator	Zhang, Chao Zhou, Dongming
Source	Medline; PMC
abstract	Adenoviral vectors are widely employed against infectious diseases or cancers, as they can elicit specific antibody responses and T cell responses when they are armed with foreign genes as vaccine carriers, and induce apoptosis of the cancer cells when they are genetically modified for cancer therapy. In this review, we summarize the biological characteristics of adenovirus (Ad) and the latest development of Ad vector-based strategies for the prevention and control of emerging infectious diseases or cancers. Strategies to circumvent the pre-existing neutralizing antibodies which dampen the immunogenicity of Ad-based vaccines are also discussed.
has issue date	2016-04-22(xsd:dateTime)
bibo:doi	10.1080/21645515.2016.1165908
bibo:pmid	27105067
has license	cc-by-nc
sha1sum (hex)	0dc8d11784da63b899dbb2b404be4efd330e4ac3
schema:url	https://doi.org/10.1080/21645515.2016.1165908
resource representing a document's title	Adenoviral vector-based strategies against infectious disease and cancer
has PubMed Central identifier	PMC4994731
has PubMed identifier	27105067
schema:publication	Hum Vaccin Immunother
resource representing a document's body	covid:0dc8d11784da63b899dbb2b404be4efd330e4ac3#body_text
is schema:about of	named entity 'cancers' named entity 'genetically modified' named entity 'responses' named entity 'cancer' named entity 'CANCER' named entity 'EMERGING INFECTIOUS DISEASES' named entity 'SPECIFIC ANTIBODY' named entity 'ADENOVIRUS' named entity 'T CELL' named entity 'CANCERS' named entity 'PRE-EXISTING' named entity 'IMMUNOGENICITY' named entity 'STRATEGIES' named entity 'INFECTIOUS DISEASES' named entity 'CHARACTERISTICS' named entity 'PREVENTION AND CONTROL' named entity 'REVIEW' named entity 'VACCINES' named entity 'APOPTOSIS' named entity 'INFECTIOUS DISEASE' named entity 'ADENOVIRAL VECTOR' named entity 'LATEST' named entity 'CANCER CELLS' named entity 'VACCINE' named entity 'INDUCE' named entity 'CARRIERS' named entity 'GENES' named entity 'DEVELOPMENT' named entity 'NEUTRALIZING ANTIBODIES' named entity 'MODIFIED' named entity 'ADENOVIRAL' named entity 'ELICIT' named entity 'BASED' named entity 'STRATEGIES' named entity 'BASED' named entity 'VECTORS' named entity 'BIOLOGICAL' named entity 'ARMED' named entity 'EMPLOYED' named entity 'RESPONSES' named entity 'FOREIGN' named entity 'CANCER THERAPY' named entity 'vectors' named entity 'adenovirus' named entity 'strategies' named entity 'infectious diseases' named entity 'Adenoviral' named entity 'genetically modified' named entity 'infectious diseases' named entity 'vaccines' named entity 'immunogenicity' named entity 'antibody' named entity 'vaccine' named entity 'Adenoviral vectors' named entity 'apoptosis' named entity 'dengue' named entity 'bacteria' named entity 'neutralizing antibodies' named entity 'influenza vaccine' named entity 'vaccine' named entity 'viral load' named entity 'vector' named entity 'viral replication' named entity 'Ebola' named entity 'CD8' named entity 'Sudan' named entity 'Ebola vaccine' named entity 'capsids' named entity 'Ebola vaccine' named entity 'tumor suppression' named entity 'ectodomain' named entity 'specialized cells' named entity 'protein' named entity 'icosahedral capsids' named entity 'glioblastoma multiforme' named entity 'antibody' named entity 'anti-cancer' named entity 'DNA vaccine' named entity 'recombinant' named entity 'vaccine'

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