About: Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Creator	Zhang, Li Zhou, Min Liu, Ying Han, Yang Qiu, Yang Wei, Yuan Qu, Jieming Chen, Nanshan Dong, Xuan Gong, Fengyun Wang, Jingli Zhang, Jia'an Xia, Ting Yu, Xinxin
Source	Elsevier; Medline; PMC
abstract	Summary Background In December, 2019, a pneumonia associated with the 2019 novel coronavirus (2019-nCoV) emerged in Wuhan, China. We aimed to further clarify the epidemiological and clinical characteristics of 2019-nCoV pneumonia. Methods In this retrospective, single-centre study, we included all confirmed cases of 2019-nCoV in Wuhan Jinyintan Hospital from Jan 1 to Jan 20, 2020. Cases were confirmed by real-time RT-PCR and were analysed for epidemiological, demographic, clinical, and radiological features and laboratory data. Outcomes were followed up until Jan 25, 2020. Findings Of the 99 patients with 2019-nCoV pneumonia, 49 (49%) had a history of exposure to the Huanan seafood market. The average age of the patients was 55·5 years (SD 13·1), including 67 men and 32 women. 2019-nCoV was detected in all patients by real-time RT-PCR. 50 (51%) patients had chronic diseases. Patients had clinical manifestations of fever (82 [83%] patients), cough (81 [82%] patients), shortness of breath (31 [31%] patients), muscle ache (11 [11%] patients), confusion (nine [9%] patients), headache (eight [8%] patients), sore throat (five [5%] patients), rhinorrhoea (four [4%] patients), chest pain (two [2%] patients), diarrhoea (two [2%] patients), and nausea and vomiting (one [1%] patient). According to imaging examination, 74 (75%) patients showed bilateral pneumonia, 14 (14%) patients showed multiple mottling and ground-glass opacity, and one (1%) patient had pneumothorax. 17 (17%) patients developed acute respiratory distress syndrome and, among them, 11 (11%) patients worsened in a short period of time and died of multiple organ failure. Interpretation The 2019-nCoV infection was of clustering onset, is more likely to affect older males with comorbidities, and can result in severe and even fatal respiratory diseases such as acute respiratory distress syndrome. In general, characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia. Further investigation is needed to explore the applicability of the MuLBSTA score in predicting the risk of mortality in 2019-nCoV infection. Funding National Key R&D Program of China.
has issue date	2020-02-21(xsd:dateTime)
bibo:doi	10.1016/s0140-6736(20)30211-7
bibo:pmid	32007143
has license	els-covid
sha1sum (hex)	0dca038ac8dfd45a921b7cd9f1c90a8554799e23
schema:url	https://doi.org/10.1016/s0140-6736%2820%2930211-7
resource representing a document's title	Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
has PubMed Central identifier	PMC7135076
has PubMed identifier	32007143
schema:publication	The Lancet
resource representing a document's body	covid:0dca038ac8dfd45a921b7cd9f1c90a8554799e23#body_text
is schema:about of	named entity 'BACKGROUND' named entity '2019 NOVEL CORONAVIRUS' named entity 'WUHAN' named entity 'DECEMBER' named entity '2019' named entity 'WUHAN' named entity 'CLARIFY' named entity 'CHINA' named entity 'EPIDEMIOLOGICAL' named entity 'CASES' named entity 'CHINA' named entity 'EPIDEMIOLOGICAL' named entity 'DESCRIPTIVE STUDY' named entity 'PNEUMONIA' named entity 'ASSOCIATED WITH' named entity '2019 NOVEL CORONAVIRUS' named entity 'CLINICAL CHARACTERISTICS' named entity 'PNEUMONIA' named entity 'CLINICAL CHARACTERISTICS' covid:arg/0dca038ac8dfd45a921b7cd9f1c90a8554799e23 named entity '2019-nCoV' named entity 'pneumonia' named entity 'pneumonia' named entity '2019' named entity '2019-nCoV' named entity 'Wuhan' named entity 'epidemiological' named entity 'pneumonia' named entity 'Epidemiological' named entity 'China' named entity 'Wuhan' named entity 'clinical characteristics' named entity 'pneumonia' named entity 'coronavirus' named entity 'coronavirus' named entity 'clinical characteristics' named entity 'descriptive study' named entity '2019-nCoV' named entity 'pneumonia' named entity 'In December' named entity '2019-nCoV' named entity 'coronavirus' named entity 'epidemiological' named entity 'Wuhan' named entity 'emerged' named entity 'Background' named entity 'China' named entity 'Wuhan' named entity 'pneumonia' named entity '2019' named entity 'cases' named entity 'China' named entity 'clarify' named entity '2019' named entity 'Epidemiological' named entity 'study' nodeID://b56491610 nodeID://b56791602 nodeID://b56919634 nodeID://b57124422 nodeID://b57166682 nodeID://b57288570 nodeID://b57413702 nodeID://b57675958 nodeID://b57741542 nodeID://b57741586 nodeID://b58055354 nodeID://b58135450

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