About: Integrated genomic view of SARS-CoV-2 in India

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Integrated genomic view of SARS-CoV-2 in India
Creator	Bala, Manju Agrawal, Anurag Singh, Priyanka Dash, Debasis Dhar, Mahesh Faruq, Mohammed Gogia, Hema Kabra, Sandhya Kumar, Pramod Lall, Hemlata Madan, Preeti Pandey, Rajesh Rakshit, Partha Saini, Nidhi Sharma, Uma Singh, Sujeet Tyagi, Nishu Vashisht, Himanshu Wadhwa, Saruchi Sharma, Pooja Kumar, Dhirendra Bag, Satyabrata Datta, Meena Deepanshi, Fatihi, Saman Gupta, Poonam Jaiswal, Varun Jatana, Nidhi Mukerji, Mitali Nandi, Bibhash Rathore, Surabhi Singh, Prateek Singh, Simrita Tewari, Aarti Thukral, Lipi Uppili, Bharathram
Source	BioRxiv
abstract	India first detected SARS-CoV-2, causal agent of COVID-19 in late January-2020, imported from Wuhan, China. March-2020 onwards; importation of cases from rest of the countries followed by seeding of local transmission triggered further outbreaks in India. We used ARTIC protocol based tiling amplicon sequencing of SARS-CoV-2 (n=104) from different states of India using a combination of MinION and MinIT from Oxford Nanopore Technology to understand introduction and local transmission. The analyses revealed multiple introductions of SARS-CoV-2 from Europe and Asia following local transmission. The most prevalent genomes with patterns of variance (confined in a cluster) remain unclassified, here, proposed as A4-clade based on its divergence within A-cluster. The viral haplotypes may link their persistence to geo-climatic conditions and host response. Despite the effectiveness of non-therapeutic interventions in India, multipronged strategies including molecular surveillance based on real-time viral genomic data is of paramount importance for a timely management of the pandemic.
has issue date	2020-06-04(xsd:dateTime)
bibo:doi	10.1101/2020.06.04.128751
has license	biorxiv
sha1sum (hex)	0e90f98d20d4b697b0cfec6f0228b969a6938252
schema:url	https://doi.org/10.1101/2020.06.04.128751
resource representing a document's title	Integrated genomic view of SARS-CoV-2 in India
schema:publication	bioRxiv
resource representing a document's body	covid:0e90f98d20d4b697b0cfec6f0228b969a6938252#body_text
is schema:about of	named entity 'variance' named entity 'MinION' named entity 'importation' named entity 'March' named entity 'tiling' named entity 'causal' named entity 'based' named entity 'transmission' named entity 'effectiveness' named entity 'genomic' named entity 'STRATEGIES' named entity 'INTRODUCTION' named entity 'AMPLICON SEQUENCING' named entity 'HERE' named entity 'LOCAL' named entity 'PROPOSED' named entity 'EUROPE' named entity 'COUNTRIES' named entity 'LINK' named entity 'FOLLOWING' named entity 'JANUARY' named entity 'TILING' named entity 'prevalent' named entity 'transmission' named entity 'strategies' named entity 'viral' named entity 'link' named entity 'The' named entity 'based' named entity 'divergence' named entity 'local transmission' named entity 'China' named entity 'MinION' named entity 'causal agent' named entity 'SARS-CoV-2' named entity 'India' named entity 'India' named entity 'MinIT' named entity 'Oxford Nanopore Technology' named entity 'haplotypes' named entity 'SARS-CoV-2' named entity 'paramount' named entity 'social distance' named entity 'India' named entity 'clade' named entity 'East Asia' named entity 'Nucleocapsid' named entity 'fasta sequences' named entity 'pathogen'

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