About: The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities

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About: The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities
Creator	Yuen, Kwok-Yung Li, Lanjuan Chen, Honglin Chan, Jasper To, Kelvin
Source	Elsevier; Medline; PMC
abstract	Summary Infection with either influenza A H5N1 virus in 1997 or avian influenza A H7N9 virus in 2013 caused severe pneumonia that did not respond to typical or atypical antimicrobial treatment, and resulted in high mortality. Both viruses are reassortants with internal genes derived from avian influenza A H9N2 viruses that circulate in Asian poultry. Both viruses have genetic markers of mammalian adaptation in their haemagglutinin and polymerase PB2 subunits, which enhanced binding to human-type receptors and improved replication in mammals, respectively. Hong Kong (affected by H5N1 in 1997) and Shanghai (affected by H7N9 in 2013) are two rapidly flourishing cosmopolitan megacities that were increasing in human population and poultry consumption before the outbreaks. Both cities are located along the avian migratory route at the Pearl River delta and Yangtze River delta. Whether the widespread use of the H5N1 vaccine in east Asia—with suboptimum biosecurity measures in live poultry markets and farms—predisposed to the emergence of H7N9 or other virus subtypes needs further investigation. Why H7N9 seems to be more readily transmitted from poultry to people than H5N1 is still unclear.
has issue date	2013-09-30(xsd:dateTime)
bibo:doi	10.1016/s1473-3099(13)70167-1
bibo:pmid	23969217
has license	els-covid
sha1sum (hex)	0fa2f3fcf3b8a5fce92ea36064ca6a458c992503
schema:url	https://doi.org/10.1016/s1473-3099%2813%2970167-1
resource representing a document's title	The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities
has PubMed Central identifier	PMC7158959
has PubMed identifier	23969217
schema:publication	The Lancet Infectious Diseases
resource representing a document's body	covid:0fa2f3fcf3b8a5fce92ea36064ca6a458c992503#body_text
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